بررسي عملكردهاي اجرايي و شناختي در بيماران دوقطبي و اعضاي خانواده آن ها

Evaluation of executive and cognitive functions in bipolar patients and their family members

سابقه و هدف اختلال دوقطبي يك اختلال روان پزشكي ناتوان كننده است كه با دوره هاي مكرر افسردگي، مانيا و هيپومانيا مشخص مي شود. تاكنون در ايران به بررسي و مقايسه عملكردهاي اجرايي و شناختي در بيماران دوقطبي و اعضاي خانواده آن ها پرداخته نشده است. هدف پژوهش حاضر، بررسي عملكردهاي اجرايي و شناختي در بيماران دوقطبي و اعضاي خانواده آن ها است. مواد و روش ها در اين مطالعه مقطعي 50 بيمار مبتلا به اختلال دوقطبي، 50 نفر از اعضاي خانواده آن ها، و 50 فرد سالم شركت كردند. از مقياس رتبه بندي مانياي يانگ، سياهه افسردگي بك، آزمون برج لندن، آزمون دسته بندي كارت ويسكانسين، آزمون ايفاي نقش، روش انداختن خط كش، آزمون چهار گزينه اي، و آزمون هوش عمومي براي بررسي عملكردهاي اجرايي و شناختي شركت كنندگان استفاده شد. نتايج عملكرد اجرايي و شناختي در اختلال دوقطبي به صورت معني داري پايين تر از گروه هاي ديگر بود (0/01

Background: Bipolar disorder is a debilitating psychiatric disorder characterized by recurrent depression, manic, and hypomanic episodes. Examination and comparison of executive and cognitive functions in bipolar patients and their family members has not been addressed in Iran so far. The aim of the present study was to examine executive and cognitive functions in bipolar patients and their family members. Materials and Methods: In this cross-sectional study, 50 patients with bipolar disorder, 50 of their family members, and 50 healthy controls were included. The Young Mania Rating Scale, Beck Depression Inventory, Tower of London task, Wisconsin Card Sorting Task, Trail Making Test, Ruler dro‎p method, Four- Choice task, and general intelligence test were used to examine executive and cognitive functions of the participants. Results: Executive and cognitive functions in patients with a bipolar disorder were significantly lower than those in the other groups (P<0.01), but there was no significant difference in executive and cognitive functions between family members of the patients and healthy controls. Conclusion: According to the results of the present study, executive and cognitive functions have been destroyed in patients with bipolar disorder, but their family members have normal executive and cognitive functions.