ﺳﺮﻃـﺎن ﭘﺴﺘﺎن ﻣـﺮدان

Male Breast Cancer

ﺯﻣﻴﻨﻪ ﻭ ﻫﺪﻑ: ﺑﺮﺭﺳﻲ ﻣﻘﺎﻻﺕ ﻭ ﺟﻤﻊ ﺁﻭﺭﻱ ﻣﻨﺎﺑﻊ ﺍﻃﻼﻋﺎﺗﻲ ﻣـﺮﺑﻮﻁ ﺑﻪ ﺳﺮﻃﺎﻥ ﺩﺭ ﻣﺮﺩﺍﻥ مواد ﻭ ﺭﻭﺵ ﻫﺎ: ﺩﺭ ﺟﺴﺘﺠﻮﻱ ﻣﻨﺎﺑﻊ ﺑﺮﺍﻱ ﺍﻳﻦ ﻣﻘﺎﻟﻪ ﺑﺎ ﺍﺷﺎﺭﻩ ﺑﻪ ﺳﺮﻃﺎﻥ ﭘﺴﺘﺎﻥ ﻣﺮﺩﺍﻥ ﺩﺭ ﻧﻴﻢ ﺩﻫﺔ ﺍﺧﻴﺮ ﺑﻴﺶ ﺍﺯ ﺩﻩ ﻫﺰﺍﺭ ﻣﻮﺭﺩ ﺍﺭﺗﺒﺎﻁ ﻛﻪ 3472 ﻣﻮﺭﺩ ﺑﻪ ﻃﻮﺭ ﻣﺴﺘﻘﻴﻢ ﻣﺮﺑﻮﻁ ﺑﻪ ﺳﺮﻃﺎﻥ ﭘﺴﺘﺎﻥ ﺩﺭ ﻣﺮﺩﺍﻥ ﺍﺳﺖ ﺍﻧﺘﺨﺎﺏ ﻭ ﺩﺭ ﻣﺠﻤﻮﻉ ﺑﻪ 198 ﻣﻘﺎﻟﻪ ﻭ ﭘﺎﻳﮕﺎﻩ ﺍﻃﻼﻋﺎﺗﻲ ﺍﺯ ﺳﺎﻝ 1982 ﺗﺎ ﺍﻭﺍﺧﺮ 2006 ﺍﺷﺎﺭﻩ ﺷﺪﻩ ﺍﺳﺖ. ﺩﺭ ﺍﻳﻦ ﻣـﺮﻭﺭ ﻧﺤﻮﺓ ﺑﻴﻤﺎﺭ ﻳﺎﺑﻲ، ﻏﺮﺑﺎﻟﮕﺮﻱ ﺗﺸﺨﻴﺼﻲ،ﺩﺭﻣﺎﻥ ﻭ ﭘﻴﺶ ﺍﮔﻬﻲ ﺩﺭ ﻣﻄﺎﻟﻌﺎﺕ ﻣﺨﺘﻠﻒ ﻣﻘﺎﻳﺴﻪ ﺷﺪﻩ ﺍﺳﺖ. ﻳﺎﻓﺘﻪ ﻫﺎ: ﺳﺮﻃﺎﻥ ﭘﺴﺘـﺎﻥ ﻣـﺮﺩﺍﻥ ﻳﻚ ﺩﺭﺻﺪ ﺍﺯ ﺳﺮﻃﺎﻥ ﻫﺎﻱ ﻣـﺮﺩﺍﻥ ﺭﺍ ﺷﺎﻣﻞ ﻣﻲ ﺷﻮﺩ. ﺍﻏﻠـﺐ ﺑﺎ ﻛﺸﻒ ﺗﻮﺩﻩ ﺍﻱ ﺑﺪﻭﻥ ﺩﺭﺩ ﻣﺮﺍﺟﻌﻪ ﻣﻲ ﻛﻨﻨﺪ. ﻣﺘﻮﺳﻂ ﺳﻦ ﺑﻴﻤـﺎﺭﺍﻥ ﺩﺭ ﻛﺸﻮﺭﻫﺎﻱ ﻣﺨﺘﻠﻒ ﺣﺪﻭﺩ 60 ﺳﺎﻝ ﺍﺳﺖ. ﻧﻮﻉ ﭘﺎﺗﻮﻟﻮﮊﻱ ﺗﻘﺮﻳﺒﺎﹰ ﻫﻤﻴﺸﻪ ﺍﺯ ﻧﻮﻉ Invasive Ductal ﺍﺳـﺖ. ﺍﺳﺘﻔـﺎﺩﻩ ﺍﺯ ﻏﺮﺑﺎﻟﮕـﺮﻱ ﻣﺎﻣﻮﮔـﺮﺍﻓﻲ ﻓﻘـﻂ ﺩﺭ ﺑﻴﻤﺎﺭﺍﻥ ﺑﺎ ﺳﺎﺑﻘﺔ ﻓﺎﻣﻴﻠﻲ ﺩﺭﺟﺔ ﺍﻭﻝ ﻳﺎ ﻣﺜﺒﺖ ﺑﻮﺩﻥ ﺑﺮﺭﺳﻲ ﻛـﺮﻭﻣﻮﺯﻭﻣﻲ ﺻﻮﺭﺕ ﻣﻲ ﮔﻴـﺮﺩ. ﺩﺭﻣﺎﻥ ﺟﺮﺍﺣﻲ ﺍﻏﻠﺐ ﺑﻪ ﺻﻮﺭﺕ ﻣﺎﺳﺘﻜﺘـﻮﻣﻲ ﺍﺻﻼﺡ ﺷـﺪﻩ ﻳﺎ ﺭﺍﺩﻳـﻜﺎﻝ ﺗﻮﺻﻴﻪ ﻣﻲ ﺷﻮﺩ ﻫﺮ ﭼﻨﺪ ﻛﻪ ﺟﺮﺍﺣﻲ ﺣﻔـﻆ ﭘﺴﺘـﺎﻥ ﻫﻢ ﻣﻄﺮﺡ ﺑـﻮﺩﻩ ﺍﺳﺖ. ﻛﺎﺭﺁﺯﻣـﺎﺋﻲ ﺑﺎﻟﻴﻨﻲ ﻭﺳﻴﻌـﻲ ﺑﺮﺍﻱ ﻣﻘﺎﻳﺴـﻪ ﺭﻭﺵ ﻫﺎﻱ ﺷﻴﻤـﻲ ﺩﺭﻣﺎﻧﻲ ﺩﺭ ﺁﻗﺎﻳﺎﻥ ﺻﻮﺭﺕ ﻧﮕـﺮﻓﺘﻪ ﻭ ﺩﺭﻣـﺎﻥ ﺩﺭ ﻣﺮﺩﺍﻥ ﻣﺸﺎﺑﻪ ﺧﺎﻧﻢ ﻫﺎ ﺍﻧﺠﺎﻡ ﻣﻲ ﮔﻴﺮﺩ. ﭘﻴﺶ ﺁﮔﻬﻲ ﻭ ﺩﺭﻣـﺎﻥ ﻇﺎﻫـﺮﺍﹰ ﻳﻜﺴﺎﻥ ﺍﺳﺖ ﻭﻟـﻲ ﺍﻏﻠﺐ ﻣـﺮﺩﺍﻥ ﺑﻪ ﻋﻠـﺖ ﻓﻘـﺪﺍﻥ ﺍﻃﻼﻋﺎﺕ ﻛﺎﻓﻲ ﺩﻳﺮ ﻣﺮﺍﺟﻌﻪ ﻣﻲ ﻛﻨﻨﺪ. ﻧﺘﻴﺠﻪ ﮔﻴـﺮﻱ: ﺍﻓﺰﺍﻳﺶ ﺁﮔـﺎﻫﻲ ﻣﺮﺩﺍﻥ، ﺍﺭﺗﻘـﺎﺀ ﻛﻴﻔﻴـﺖ ﺑـﺮﺭﺳﻲ ﺍﻳﻦ ﺑﻴﻤـﺎﺭﻱ ﺩﺭ ﻣـﺮﺩﺍﻥ ﻭ ﺁﻣـﻮﺯﺵ ﻫﺎﻱ ﻫﻤـﮕﺎﻧﻲ ﺿـﺮﻭﺭﻱ ﺍﺳﺖ.

Introduction & Objective: To review the articles and data sources published on male breast cancer. Materials & Methods: Searching for male breast cancer in recent half decade results in more than 10000 – links leading to 3472 chosen direct sours for male breast cancer which among 198 articles and web sites from 1982 to 2006 has been mentioned. In this review; screening, diagnostic tools, surgery and adjuvant therapy and also the prognosis has been analyzed. Results: Male breast carcinomas are 1% of male carcinomas, often presented with painless tumor and mean age of 60 world wide. Screen mammography is advisable only in first degree related breast carcinoma cases and in genetic positive ones. Advised surgical procedure is mastectomy either modified or radical and some case series rare reported conserving method. There are not clinical trials comparing different chemotherapy regimes in male patients and so the adjuvant in males is the same as women. Prognosis is the same as in females but males are diagnosed in later stages due to less informed concepts. Conclusions: Increase in attitude and approach quality in men is indicated.