ﺑﺮرﺳﯽ ﻣﯿﺰان آﻟﻮدﮔﯽ ﺑﺎ دﯾﮑﺮوﺳﻮﻟﯿﻮم دﻧﺪرﯾﺘﯿﮑﻮم ﮔﻮﺳﻔﻨﺪ و ﺑﺰ ﮐﺸﺘﺎري در ﮐﺸﺘﺎرﮔﺎه ﻫﺎي ﺷﻬﺮﺳﺘﺎن ﻫﺎي ﻧﺠﻒآﺑﺎد و ﻟﻨﺠﺎن در اﺳﺘﺎن اﺻﻔﻬﺎن و ﺑﺮرﺳﯽ ﺿﺎﯾﻌﺎت آﺳﯿﺐ ﺷﻨﺎﺳﯽ ﻧﺎﺷﯽ از آن در ﮐﺒﺪ

Investigation of the Prevalence of Dicrocolium dendriticum Infection in Sheep and Goat s in Slaughterhouses of Najafabad and Lanjan in Isfahan Province and Evaluation of Its Pathologic Lesions in the Liver

دﯾﮑﺮوﺳﻠﯿﺎزﯾﺲ ﺑﯿﻤﺎري ﺷﺎﯾﻊ در ﻧﺸﺨﻮارﮐﻨﻨﺪﮔﺎن اﺳﺖ ﮐﻪ ﺗﻮﺳﻂ ﮔﻮﻧﻪ ﻫﺎي ﻣﺨﺘﻠﻒ دﯾﮑﺮوﺳﻠﯿﻮم اﯾﺠﺎد ﻣﯽ ﺷﻮد. اﯾﻦ اﻧﮕﻞ در ﻣﺠﺎري ﺻﻔﺮاوي و ﮐﯿﺴﻪ ﺻﻔﺮاي ﻧﺸﺨﻮارﮐﻨﻨﺪﮔﺎن و ﮔﺎﻫﯽ ﺑﻪ ﻃﻮر ﺗﺼﺎدﻓﯽ در اﻧﺴﺎن دﯾﺪه ﻣﯽ ﺷﻮد. اﻫﻤﯿﺖ اﻗﺘﺼﺎدي و داﻣﭙﺰﺷﮑﯽ دﯾﮑﺮوﺳﻠﯿﺎزﯾﺲ ﺑﻪ ﻋﻠﺖ ﺧﺴﺎرت ﻣﺴﺘﻘﯿﻢ ﺑﻪ ﮐﺒﺪ و در ﻧﺘﯿﺠﻪ از دﺳﺖ دادن ﻣﻘﺎدﯾﺮ ﻗﺎﺑﻞ ﺗﻮﺟﻬﯽ از ﻣﻮاد ﭘﺮوﺗﺌﯿﻨﯽ ﺑﺎ ارزش از رژﯾ ﻏﺬاﯾﯽ اﻧﺴﺎن ﺑﻪ ﻋﻠﺖ ﺣﺬف ﮐﺒﺪﻫﺎي آﻟﻮده در ﮐﺸﺘﺎرﮔﺎه ﻫﺎ ﻣﯽ ﺑﺎﺷﺪ. ﻣﯿﺰﺑﺎﻧﺎن واﺳﻂ اﯾﻦ اﻧﮕﻞ ﺣﻠﺰونﻫﺎي ﺧﺎﮐﯽ )ﻣﯿﺰﺑﺎن ا ﻣ رﭼﻪﻫﺎﯾﯽ ﺑﻪ ﻧﺎم ﻓﻮرﻣﯿﮑﺎ )ﻣﯿﺰﺑﺎن دوم( ﻣﯽ ﺑﺎﺷﻨﺪ. ﺑﻪ ﻣﻨﻈﻮر ﺑﺮرﺳﯽ ﻣﯿﺰان ﺷﯿﻮع آﻟﻮدﮔﯽ ﺑﺎ دﯾﮑﺮوﺳﻮﻟﯿﻮم دﻧﺪرﯾﺘﯿﮑﻮم در ﮔﻮﺳﻔﻨﺪ ﺑﺰ ﮐﺸﺘﺎري ﮐﺸﺘﺎرﮔﺎه ﻫﺎي ﺷﻬﺮﺳﺘﺎن ﻟﻨﺠﺎن و ﻧﺠﻒ آﺑﺎد ﺑﻪ ﻣﺪت ﯾﮏ ﺳﺎل در ﭼﻬﺎر ﻓﺼﻞ )ﭘﺎﺋﯿﺰ، زﻣﺴﺘﺎن، ﺑﻬﺎر و ﺗﺎﺑﺴﺘﺎن( از ﺗﻌﺪاد 131521 ﮐﺒﺪ ﮔﻮﺳﻔﻨﺪي و 19672 ﮐﺒﺪ ﺑﺰي ﻣﻮرد ﺑﺎزرﺳﯽ ﺷﺪه در ﮐﺸﺘﺎرﮔﺎه ﻧﺠﻒ آﺑﺎد ﺑﻪ ﺗﺮﺗﯿﺐ ﺗﻌﺪاد 4660 و 193 ﮐﺒﺪ ﺳﻔﻨﺪي و ﺑﺰي آﻟﻮده ﺑﻪ اﻧﮕﻞ دﯾﮑﺮوﺳﻮﻟﯿﻮم و از ﺗﻌﺪاد 45713 ﮐﺒﺪ ﮔﻮﺳﻔﻨﺪي و 3726 ﮐﺒﺪ ﺑﺰي ﺑﺎزرﺳﯽ ﺷﺪه در ﮐﺸﺘﺎرﮔﺎ ﺠﺎن ﺑﻪ ﺗﺮﺗﯿﺐ ﺗﻌﺪاد 4281 و 72 ﮐﺒﺪ ﮔﻮﺳﻔﻨﺪي و ﺑﺰي آﻟﻮده ﺑﻪ اﻧﮕﻞ دﯾﮑﺮوﺳﻮﻟﯿﻮم ﺑﻮد. ﺗﻌﺪاد 30 ﻧﻤﻮﻧﻪ ﮐﺒﺪ آﻟﻮده ﺟﻬﺖ ﻣﻄﺎﻟﻌﺎت ﻫﯿﺴﺘﻮﭘﺎﺗﻮﻟﻮژﯾﮏ ﺟﻤﻊ آوري و ﺑﻌﺪ از ﻣﺮاﺣﻞ ﺗﻬﯿﻪ ﻻم و رﻧﮓ آﻣﯿﺰي ﺑﻪ روش ﻫﻤﺎﺗﻮﮐﺴﯿﻠﯿﻦ و اﺋﻮزﯾﻦ ﻣﻮرد ﺑﺮرﺳﯽ ﻗﺮار ﮔﺮﻓﺘﻨﺪ ﮐﻪ در ﻧﺘﯿﺠﻪ در اﺛﺮ آﻟﻮدﮔﯽ ﮐﺒﺪﻫﺎ ﺑﺎ اﻧﮕﻞ، ﺗﺨﺮﯾﺐ ﺑﺎﻓﺖ ﮐﺒﺪ، ﺗﺸﮑﯿﻞ ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ وﺳﯿﻊ، ﻫﯿﭙﺮﭘﻼزي ﻣﺠﺎري ﺻﻔﺮاوي ﺮاه ﺑﺎ ﺗﺸﮑﯿﻞ ﮔﺮاﻧﻮﻟﻮم، ﻧﮑﺮوز ﺑﺎﻓﺖ ﮐﺒﺪي، ﺣﻀﻮر ﺳﻠﻮل ﻫﺎي آﻣﺎﺳﯽ در ﺑﺎﻓﺖ و ﮐﻠﺴﯿﻔﯿﮑﺎﺳﯿﻮن ﻗﺎﺑﻞ ﻣﺸﺎﻫﺪه ﺑﻮد.

Dicloleosis is the common disease among ruminants that is caused by different dicrocolemia species. This parasite is observed in the bile duct and gallblader of the ruminants and randomly in humans. The economic and veterinary significance of Dicrocoelium is due to its direct damage to the liver, resulting in the loss of significant amounts of valuable protein substances from human diets due to the elimination of contaminated liver in slaughterhouses. The intermediate hosts of this parasite are earthworms (the first hosts) and ant Formaica (the second host). In order to investigate the prevalence of Dicrocoelium dendriticum infection in sheep and goat in slaughterhouses of Lenjan and Najafabad for four seasons (autumn-winter, spring and summer) of 131521 sheep livers and 19672 goat livers inspected in Najafabad slaughterhouse, 4660 and 193 sheep and goat livers were infected by dicorrosilum parasites. moreover, of 45713 sheep livers and 3726 goat livers inspected in the Lanjan slaughterhouse, 4281 and 72 sheep and goat livers were infected by Dicrocoelium parasite, respectively. A total of 30 infected liver samples were collected for histopathologic studies and then they were examined after lamination and staining with hematoxylin and eosin method. As a result of liver infections, liver tissue destruction, enlarged connective tissue, bile duct hyperplasia, formation of granuloma, liver tissue necrosis, presence of inflammatory cells in tissue and calcification were observed.