ﺗﺄﺛﯿﺮ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺑﺮ ﺳﻄﻮح ﭘﻼﺳﻤﺎﯾﯽ اﺳﯿﺪﻫﺎي آﻣﯿﻨﻪي ﺷﺎﺧﻪدار و ﻣﻘﺎوﻣﺖ ﺑﻪ اﻧﺴﻮﻟﯿﻦ در ﭘﺴﺮان ﻧﻮﺟﻮان ﭼﺎق

The Effect of Circuit Resistance Training on the Plasma Levels of Branched-Chain Amino Acids and Insulin Resistance in Obese Adolescents Boys

ﺳﺎﺑﻘﻪ و ﻫﺪف: ﺳﻄﻮح اﺳﯿﺪﻫﺎي آﻣﯿﻨﻪ ﺷﺎﺧﻪدار در اﻓﺮاد ﭼﺎق اﻓﺰاﯾﺶ ﻣﯽﯾﺎﺑﺪ و ﺑﺎ ﻣﻘﺎوﻣﺖ ﺑﻪ اﻧﺴﻮﻟﯿﻦ و دﯾﺎﺑﺖ ﻧﻮع 2 ﻣﺮﺗﺒﻂ اﺳﺖ. ﻫﺪف از ﺗﺤﻘﯿﻖ ﺣﺎﺿﺮ ﺑﺮرﺳﯽ ﺗﺄﺛﯿﺮ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺑﺮ ﺳﻄﻮح ﭘﻼﺳﻤﺎﯾﯽ اﺳﯿﺪﻫﺎي آﻣﯿﻨﻪي ﺷﺎﺧﻪدار و ﻣﻘﺎوﻣﺖ ﺑﻪ اﻧﺴﻮﻟﯿﻦ در ﭘﺴﺮان ﻧﻮﺟﻮان ﭼﺎق ﺑﻮد. ﻣﻮاد و روشﻫﺎ: 33 ﭘﺴﺮ ﻧﻮﺟﻮان ﭼﺎق (30≥BMI) ﺑﺎ داﻣﻨﻪ ﺳﻨﯽ 14-17 ﺳﺎل ﺑﻪﺻﻮرت ﺗﺼﺎدﻓﯽ ﺑﻪ دو ﮔﺮوه ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي (16 ﻧﻔﺮ)و ﮐﻨﺘﺮل (17 ﻧﻔﺮ) ﺗﻘﺴﯿﻢ ﺷﺪﻧﺪ. ﺑﺮﻧﺎﻣﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺑﻪ ﻣﺪت 8 ﻫﻔﺘﻪ، ﺳﻪ ﺟﻠﺴﻪ در ﻫﻔﺘﻪ اﺟﺮا ﮔﺮدﯾﺪ. ﺑﺮﻧﺎﻣﻪ ﺗﻤﺮﯾﻨﯽ ﺷﺎﻣﻞ 11 اﯾﺴﺘﮕﺎه ﺑﻮد. ﺗﻤﺮﯾﻦ در 4 ﻫﻔﺘﻪ اول ﻃﯽ 2 ﺳﺖ ﺑﺎ 75-%70 ﯾﮏ ﺗﮑﺮار ﺑﯿﺸﯿﻨﻪ، 12-10 ﺗﮑﺮار و در 4 ﻫﻔﺘﻪ دوم ﻃﯽ 4 ﺳﺖ ﺑﺎ %80-75 ﯾﮏ ﺗﮑﺮار ﺑﯿﺸﯿﻨﻪ، 8-6 ﺗﮑﺮار اﺟﺮا ﺷﺪ. ﻓﺎﺻﻠﻪ اﺳﺘﺮاﺣﺘﯽ ﺑﯿﻦ اﯾﺴﺘﮕﺎهﻫﺎ و ﺳﺖﻫﺎ ﺑﻪ ﺗﺮﺗﯿﺐ 30 و 180 ﺛﺎﻧﯿﻪ ﺑﻮد. ﺑﺮاي اﻧﺪازهﮔﯿﺮي ﺳﻄﻮح ﭘﻼﺳﻤﺎﯾﯽ اﺳﯿﺪﻫﺎي آﻣﯿﻨﻪ ﺷﺎﺧﻪدار از روش HPLC اﺳﺘﻔﺎده ﺷﺪ. ﯾﺎﻓﺘﻪﻫﺎ: در ﻣﻘﺎﯾﺴﻪ ﺑﺎ ﮔﺮوه ﮐﻨﺘﺮل، ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﻣﻮﺟﺐ ﮐﺎﻫﺶ وزن (P<0/001) BMI ،(P<0/001)، ﮔﻠﻮﮐﺰ (P=0/035)، واﻟﯿﻦ (P=0/007) و ﻣﺠﻤﻮع اﺳﯿﺪﻫﺎي آﻣﯿﻨﻪ ﺷﺎﺧﻪدار (P=0/007) ﮔﺮدﯾﺪ و ﮐﺎﻫﺶ ﺷﺎﺧﺺ ﻣﻘﺎوﻣﺖ ﺑﻪ اﻧﺴﻮﻟﯿﻦ ﺑﻪ ﺳﻄﺢ ﻣﻌﻨﺎدار ﻧﺮﺳﯿﺪ )P=0/083(. ﻧﺘﯿﺠﻪﮔﯿﺮي: ﺗﻤﺮﯾﻨﺎت ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي در ﻧﻮﺟﻮاﻧﺎن ﭼﺎق ﻣﻨﺠﺮ ﺑﻪ ﺑﻬﺒﻮد ﺳﻄﻮح اﺳﯿﺪﻫﺎي آﻣﯿﻨﻪ ﺷﺎﺧﻪدار ﭘﻼﺳﻤﺎ، ﮔﻠﻮﮐﺰ و ﻣﻘﺎوﻣﺖ ﺑﻪ اﻧﺴﻮﻟﯿﻦ ﻣﯽﺷﻮد. ﺑﺎ ﺗﻮﺟﻪ ﺑﻪ اﯾﻨﮑﻪ ﮐﻮدﮐﺎن و ﻧﻮﺟﻮاﻧﺎن ﭼﺎق ﺑﯿﺸﺘﺮ در ﻣﻌﺮض اﺑﺘﻼ ﺑﻪ ﺑﯿﻤﺎريﻫﺎي ﻣﺨﺘﻠﻒ ﻧﻈﯿﺮ دﯾﺎﺑﺖ ﻫﺴﺘﻨﺪ، اﺣﺘﻤﺎﻻً ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺑﺘﻮاﻧﺪ از اﺑﺘﻼ ﺑﻪ اﺧﺘﻼﻻت ﻣﺘﺎﺑﻮﻟﯿﮏ ﻣﺮﺗﺒﻂ ﺑﺎ ﭼﺎﻗﯽ ﭘﯿﺸﮕﯿﺮي ﮐﻨﺪ.

Background & Purpose: The levels of branched-chain amino acids, an increase in obese subjects and associated with the risk of insulin resistance, and type 2 diabetes. The purpose of this study was to investigate the effect of circuit resistance training on the plasma levels of branched-chain amino acids and insulin resistance in in obese adolescents boys. Methodology: 33 obese adolescent boys (BMI≥30) with 14 to 17 years of age were randomly divided into two groups: Circuit resistance training group (n=16) and control group (n=17). The circuit resistance training was performed for eight-weeks, three sessions per week. The training program included 11 stations. The exercise was performed in the first 4 weeks with 2 sets with 70 -75% one repetition maximum, 10-12 repetitions, and in the second 4 weeks with 4 sets with 75-80% one repetition maximum, 6-8 replications. The rest between stations and sets was 30 and 180 seconds, respectively. HPLC method was used to measure the plasma levels of branched-chain amino acids. Results: resistance training reduced weight (P <0.001), BMI (P <0.001), glucose (P = 0.035), valine (P = 0.007) and sum of branched-chain amino acids (P = 0.007) and insulin resistance index did not reach significant level (P = 0.083). Conclusion: The circuit resistance training in obese adolescents improved levels of branched-chain amino acids, glucose, and insulin resistance. Given that obese children and adolescents are more at risk for various diseases, such as diabetes, circuit resistance training may prevent metabolic disorders associated with obesity