تاثير هشت هفته تمرين مقاومتي دايره اي بر سطوح اينترلوكين 15، IGF-I و IGFBP-3 در مردان داراي اضافه وزن

The Effect of 8 Weeks of Circuit Resistance Training on the Levels of Interleukin-15, IGF-I and IGFBP-3 in Overweight Men

اﯾﻨﺘﺮﻟﻮﮐﯿﻦ 15 )15-IL( از ﺳﺎﯾﺘﻮﮐﺎﯾﻦﻫﺎي ﻣﻬﻤﯽ اﺳﺖ ﮐﻪ ﺗﻮﺳﻂ ﻋﻀﻠﮥ اﺳﮑﻠﺘﯽ و در ﭘﺎﺳﺦ ﺑﻪ ﻓﻌﺎﻟﯿﺖ ورزﺷﯽ ﺗﺮﺷﺢ ﻣﯽﺷﻮد و ﺗﺄﺛﯿﺮات ﻣﺘﻌﺪدي ﺑﺮ ﺑﺎﻓﺖﻫﺎي ﻣﺨﺘﻠﻒ از ﺟﻤﻠﻪ ﺑﺎﻓﺖ ﻋﻀﻼﻧﯽ دارد. ﭘﮋوﻫﺶ ﺣﺎﺿﺮ ﺑﻪﻣﻨﻈﻮر ﺑﺮرﺳﯽ ﺗﺄﺛﯿﺮ 8 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺑﺮ ﺳﻄﻮح ﺳﺮﻣﯽ 15-IL در ﻣﺮدان ﺟﻮان داراي اﺿﺎﻓﻪوزن ﺻﻮرت ﮔﺮﻓﺖ. 20 ﻣﺮد ﺟﻮان داراي اﺿﺎﻓﻪوزن )BMI: 26.32±0.98 kg.m2، ﺳﻦ: 27/49±4/14 ﺳﺎل، وزن: 80/18±4/95 ﮐﯿﻠﻮﮔﺮم( ﺑﻪﺻﻮرت ﺗﺼﺎدﻓﯽ ﺑﻪ دو ﮔﺮوه )10=n( ﮐﻨﺘﺮل و ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺗﻘﺴﯿﻢ ﺷﺪﻧﺪ. ﺑﺮﻧﺎﻣﮥ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﺑﻪ ﻣﺪت 8 ﻫﻔﺘﻪ و 3 ﺟﻠﺴﻪ در ﻫﻔﺘﻪ اﺟﺮا ﺷﺪ. ﻫﺮ ﺟﻠﺴﮥ ﺗﻤﺮﯾﻦ ﺷﺎﻣﻞ 9 ﺣﺮﮐﺖ ﺑﻮد ﮐﻪ ﺑﺎ ﺷﺪت 50 ﺗﺎ 60 درﺻﺪ 1RM اﺟﺮا ﻣﯽﺷﺪ. ﻃﯽ اﯾﻦ ﻣﺪت، آزﻣﻮدﻧﯽﻫﺎي ﮔﺮوه ﮐﻨﺘﺮل ﻧﯿﺰ ﺑﺮﻧﺎﻣﮥ ﻋﺎدي روزاﻧﻪ را اداﻣﻪ دادﻧﺪ. ﭘﯿﺶ و ﭘﺲ از 48 ﺳﺎﻋﺖ از آﺧﺮﯾﻦ ﺟﻠﺴﮥ ﺗﻤﺮﯾﻦ ﺑﻪ ﻣﯿﺰان 7 ﻣﯿﻠﯽﻟﯿﺘﺮ از ورﯾﺪ ﺑﺎزوﯾﯽ آزﻣﻮدﻧﯽﻫﺎ ﺟﻬﺖ ﺑﺮآورد ﻣﺘﻐﯿﺮﻫﺎي ﻣﻮرد ﺑﺮرﺳﯽ )15-IGF-I ،IL و IGFBP3( ﺧﻮنﮔﯿﺮي ﺑﻪﻋﻤﻞ آﻣﺪ. ﯾﺎﻓﺘﻪﻫﺎ ﻧﺸﺎن داد، ﺗﻐﯿﯿﺮات در ﺳﻄﻮح 15-IGF-I ،IL و 3-IGFBP ﺑﯿﻦ دو ﮔﺮوه ﮐﻨﺘﺮل و ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي از ﻧﻈﺮ آﻣﺎري ﻣﻌﻨﺎدار ﻧﺒﻮده اﺳﺖ )0/05>P(. ﺑﺎ وﺟﻮد اﯾﻦ، درﺻﺪ ﭼﺮﺑﯽ ﺑﺪن در ﮔﺮوه ﺗﻤﺮﯾﻦﮐﺮده در ﻣﻘﺎﯾﺴﻪ ﺑﺎ ﮔﺮوه ﮐﻨﺘﺮل، ﮐﺎﻫﺶ ﻣﻌﻨﺎداري ﻧﺸﺎن داد )0/003=P(. ﺑﺮاﺳﺎس ﯾﺎﻓﺘﻪﻫﺎي ﺣﺎﺿﺮ ﻣﯽﺗﻮان ﮔﻔﺖ ﮐﻪ ﺗﺄﺛﯿﺮات ﻣﺜﺒﺖ اﺣﺘﻤﺎﻟﯽ ﺗﻤﺮﯾﻨﺎت ﻣﻘﺎوﻣﺘﯽ داﯾﺮهاي ﻃﯽ ﻣﺪت 8 ﻫﻔﺘﻪ در ﻣﺮدان ﺟﻮان داراي اﺿﺎﻓﻪوزن از ﻃﺮﯾﻖ ﻣﺴﯿﺮﻫﺎي دﯾﮕﺮي ﻏﯿﺮ از ﺗﻐﯿﯿﺮ در ﺳﻄﻮح ﻣﺘﻐﯿﺮﻫﺎي ﻣﻮرد ﺑﺮرﺳﯽ از ﺟﻤﻠﻪ 15-IL اﺗﻔﺎق ﻣﯽاﻓﺘﺪ.

Interleukin-15 (IL-15) is an important cytokine that is secreted from skeletal muscles in response to exercise and has various effects on different tissues such as muscular tissue. The present study was conducted to investigate the effect of 8 weeks of circuit resistance training on serum levels of IL-15 in young overweight men. 20 overweight young men (BMI: 26.32±0.98 kg.m2, age: 27.49±4.14 years, weight: 80.18±4.95 kg) were randomly divided into two control and circuit resistance training groups (each group 10 subjects). Circuit resistance training program was performed for 8 weeks and 3 sessions per week. Each training session consisted of 9 exercises that were performed with 50-60% 1RM. During this period, the subjects in the control group continued their routine daily program. Before and 48 hours after the last training session, 7 ml of blood samples were collected from brachial vein in order to estimate the desired variables (IL-15, IGF-I and IGFBP3). The findings indicated that changes in the levels of IL-15, IGF-I and IGFBP-3 were not statistically significant between the control and circuit resistance training groups (P>0.05). However, body fat percent indicated a significant decrease in the training group compared with the control group (P=0.003). According to these findings, it can be stated that the probable positive effects of circuit resistance training during 8 weeks in overweight young men are mediated by pathways other than the changes in the levels of the studied variables including IL-15.