مقايسة تأثير تمرين مقاومتي با و بدون محدوديت جريان خون بر ميزان IGF-1، تستوسترون و مايونكتين سرمي مردان جوان

Comparison of the effect of resistance training with and without blood flow restriction on serum levels of IGF-1, testosterone and mayonetin in young men

ﺷﯿﻮهﻫﺎي ﺗﻤﺮﯾﻨﯽ ﻣﺘﻔﺎوت ﻣـﯽﺗﻮاﻧـﺪ اﺛـﺮ ﻣﺘﻔـﺎوﺗﯽ ﺑـﺮ ﻣﯿﺰان و ﭘﺎﺳﺦ ﻫﻮرﻣﻮنﻫﺎ داﺷﺘﻪ ﺑﺎﺷﺪ. ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﻫﻤﺮاه ﺑﺎ ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن، ﯾﮑﯽ از روشﻫﺎي ﺗﻤﺮﯾﻨﯽ اﺳﺖ ﮐﻪ ﺑﻪ اﻓﺰاﯾﺶ ﻋﻤﻠﮑﺮد و ﻗﺪرت ﻋﻀﻼﻧﯽ ﻣﻨﺠﺮ ﻣﯽﺷﻮد. ﺑﻨﺎﺑﺮاﯾﻦ ﻫﺪف از اﯾﻦ ﭘﮋوﻫﺶ، ﻣﻘﺎﯾﺴﮥ ﺗﺄﺛﯿﺮ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﺎ و ﺑﺪون ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن ﺑﺮ ﻣﯿﺰان 1-IGF، ﺗﺴﺘﻮﺳﺘﺮون و ﻣﺎﯾﻮﻧﮑﺘﯿﻦ ﺳﺮﻣﯽ ﻣﺮدان ﺟﻮان ﺑﻮد. ﮔﺮوهﻫﺎي ﭘﮋوﻫﺶ ﺷﺎﻣﻞ دو ﮔﺮوه ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن )10 ﻧﻔﺮ( و ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﺪون ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن )10 ﻧﻔﺮ( ﺑﻮد. ﺑﺮﻧﺎﻣﮥ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﻪ ﻣﺪت ﭼﻬﺎر ﻫﻔﺘﻪ اﻧﺠﺎم ﮔﺮﻓﺖ. در دو ﻣﺮﺣﻠﮥ ﭘﯿﺶآزﻣﻮن و ﭘﺲآزﻣﻮن، ﻏﻠﻈــﺖ ﺳــﺮﻣﯽ 1-IGF، ﺗﺴﺘﻮﺳﺘﺮون و ﻣﺎﯾﻮﻧﮑﺘﯿﻦ ﺑﻪ روش اﻻﯾﺰا اﻧﺪازهﮔﯿﺮي ﺷﺪ. ﺑﻪﻣﻨﻈﻮر ﺗﻌﯿﯿﻦ ﻣﻌﻨﺎداري ﺗﻔﺎوت ﺑﯿﻦ ﻣﺘﻐﯿﺮﻫﺎي ﭘﮋوﻫﺶ از آزﻣﻮن ﺗﺤﻠﯿﻞ ﮐﻮوارﯾﺎﻧﺲ ﯾﮑﻄﺮﻓﻪ در ﺳﻄﺢ ﻣﻌﻨﺎداري 0/05 اﺳﺘﻔﺎده ﺷﺪ. ﯾﺎﻓﺘﻪﻫﺎ ﻧﺸﺎن داد ﮐﻪ ﻣﯿﺰان 1-IGF و ﺗﺴﺘﻮﺳﺘﺮون در ﮔﺮوه ﺗﻤﺮﯾﻦ ﺑﺎ ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن ﻧﺴﺒﺖ ﺑﻪ ﮔﺮوه ﺗﻤﺮﯾﻦ ﺑﺪون ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن، اﻓﺰاﯾﺶ ﻣﻌﻨﺎداري )0/001=P( دارد، ﺑﺎ اﯾﻦ ﺣﺎل، در ﻣﯿﺰان ﻣﺎﯾﻮﻧﮑﺘﯿﻦ اﻓﺰاﯾﺶ ﻏﯿﺮﻣﻌﻨﺎداري ﻣﺸﺎﻫﺪه ﺷﺪ )0/08=P(. اﯾﻦ ﯾﺎﻓﺘﻪﻫﺎ ﻧﺸﺎن ﻣﯽدﻫﺪ ﮐﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﻫﻤﺮاه ﺑﺎ ﻣﺤﺪودﯾﺖ ﺟﺮﯾﺎن ﺧﻮن، در ﺑﻬﺒﻮد ﻋﻮاﻣﻞ ﻣﺮﺗﺒﻂ ﺑﺎ اﻓﺰاﯾﺶ ﺣﺠﻢ ﻋﻀﻼﻧﯽ ﺑﺴﯿﺎر ﻣﺆﺛﺮ اﺳﺖ.

Different training programs have different effects on the level of hormonal response. Resistance training with blood flow restriction is one of the exercise method that leads to increase in muscle strength and performance. Therefore, the purpose of this study was to compare the effect of resistance training with and without blood flow restriction on the serum levels of IGF-1, testosterone and myonectin in young men. The research groups consisted of two groups: resistance training with blood flow restriction (10 subjects) and resistance training without blood flow restriction (10 subjects). The resistance training program was conducted for four weeks. In pre/post-test, serum concentration of IGF-1, testosterone and Myonectine was measured by ELISA method. To determine the difference between the variables, one-way covariance analysis was used at the significance level of 0/05. Our results showed that IGF-1 and testosterone levels in the exercise group with blood flow restriction were significantly higher than the exercise group without blood flow restriction (P = 0.001). However, there was a non-significant increase in myonectin levels (P = 0.08). These findings suggest that resistance training with blood flow restriction is very effective in increasing hypertrophy-related factors.