پديد آورندگان :
Barazandeh Ahmadabadi, Fateme Department of Internal Medicine - Allame Bohlool Hospital - Gonabad University of Medical Sciences, Gonabad, Iran , Ghorbani, Mohammad University of Medical Sciences, Gonabad, Iran , Niazkar, Hamid Reza Gonabad University of Medical Sciences, Gonabad, Iran , Homapour, Farhad Department of Medicine - Gonabad University of Medical Sciences, Gonabad, Iran , Nazarzade, Hedie Research Center for Iranian Academic Center for Education - Culture, and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran , Rezaei, Alireza Islamic Azad University of Medical Science, Mashhad, IR Iran , Moshari، Jalil Department of Pediatrics - School of Medicine - Gonabad University of Medical Sciences, Gonabad, Iran
كليدواژه :
Gastroenteritis , Eosinophilic Gastroenteritis , Colitis , IgA
چكيده لاتين :
Eosinophilic gastroenteritis is a rare disease with unknown etiology. It is characterized by the eosinophilic infiltration of one or more
layers of the gastrointestinal tract. Recently, the authors visited a rare case of eosinophilic gastroenteritis. A 30-year-old woman was
admitted to our hospital complaining of acute-onset excessive abdominal pain in the periumbilical region and chronic diarrhea. Physical
examination revealed a distended abdomen with tenderness. Complete blood count showed moderate eosinophilia with elevated IgA
serum levels. Computed tomography of the abdomen and pelvis was normal. Upper endoscopy (with taking biopsy samples from the
stomach and duodenum) and total colonoscopy (with taking biopsy sample from the rectum and ascending colon) were performed.
The pathological examination showed a non-destructive colitis with increased mucosal eosinophilia throughout the entire thickness
of the ascending colon and duodenum. Rectal and gastric biopsy samples did not show any signs of eosinophilic infiltration. After
ruling out of other causes of eosinophilia, eosinophilic gastroenteritis was diagnosed. The patient recovered well after treatment with
prednisone (40 mg/day) over two weeks and was free from gastrointestinal symptoms at the time we reported her disease.