سطح خوني هورمون پرولاكتين در زنان 14 تا 35 سال مبتلا به آكنه متوسط و شديد و مقايسه آن با زنان سالم

Serum Prolactin Level in Acne Patients Versus Control Group:Study on 14 to 35 Years Old Women

Introduction. Androgens have a main role in acne pathogenesis. The interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Methods. In a case - control study, 71 women with moderate to severe acne were compaired with 71 healthy women about their serum prolactin levels. Results. Mean of serum prolactin level was 533 632 miullit in cases. Mean of serum prolactin level was 365 363 in control group (P>0.05). There was a significant correlation between serum prolactin level and severity of acne. Discussion. Despite the non significant difference between serum prolactin level in acne patients and healthy women, thare was a significant relationship between serum prolactin level and severity of acne. It may be due to our small sample size. However, the more powerful studies is needed.