كارآيي تعيين مقدار اربيلي روبين بند ناف در تشخيص زردي غير طبيعي

Identifying the Newborns at Risk for Developing Significant Hyperbilirubinemia by Measuring Cord Bilirubin Levels

Backgrunds: Jaundice is mostly benign, the becase of the potential of bilirubin toxicty. Noonates should be monitored carefully for developing severe hyperbilirubinemia. The need to recognize infanis who are at risk for significant jaundiee apparent in the era of routne early diseharge. The aim of this prospective study is to identity healthy newborns at risk for developing a significant by perbilirubinemia by measuring bilirubin level in eord blood. Methods and materials: Umbilical cord serum bilirubin concentration was analyzed in 643 full term newborns at Mahdieh Hospital. Tehran, Iran , with birth weght> 2500 grams and an Apgar score >7. There were also no signs of eehymosis, cephalohematoma, septicemia, and I or premature rupture of membrane in none of the infants in this study. Bilirubin level was obtained at day three of age and total bilirubin > 14 mgldl was defined as signifieant hyperbilirubinemia. Data have been analyzed using t-test, chisquare, and Receiver Operating Characteristies (ROC) curve. Resalts: tatistically significant relation between use of Oxylocin and subseqent. Significant hyperbilirubinema (p<0.04). 92.4% of neonates with cord bilirubin level below 3 mgldl would not develop significant hyperbilirubinemia. Cord bilirubin level above 3 mg/dl is not a useful predictor of neonatal jaundice. Conelusion: Cord bilirubin level cannot identify newborns with subsequent significant hyperbilirubinema. Rally discharged neonates need close follow up and use of any other stratcgice to identify newborns at high risk of jaundice.