بررسي اپيدميولوژي ليشمانيوز احشايي (كالا آزار) در منطقه كردان از شهرستان ساوجيلاغ استان تهران

Epidemiology of visceral leishmaniosis in Kordan, Tehran

Background: Following the definite diagnosis of visceral leishmaniosis in a six-year old Doberman dog and isolation of Leishmania Infantum in Kordan in 1995, thorough studies have been carried out to determine the visceral leishmaniosis infection in human and animal reservoirs (dog), meanwhile, landflies were collected for determination of species, seasonal activities and anthropophilic activities in Kordan district. Materials and methods: During this cross sectional study, 925 human plasma sample and 21 dog plasma samples were tested by direct agglutination test (DAT) and latex agglutination test (LAT). Meanwhile, 2090 sandflies were collected. Results: A child with clinical features of leishmaniosis was seropositive. He was treated by Glucantimc and recovered completely. Three dogs showed antileishmania antibodies against visceral leishmaniosis with >1:320 titers. Seven species of Phlebotumus genus and two species of Seregentomia genus were confirmed in this investigation. The majority species were Phlebotumus major. 356 sandflies were dissected but no promastigote was found. Conclusion: Totally, one child and three dogs were revealed to be seropositive. Thus, Kala-azar is sporadic in Kordan region.