بررسي شيوع نشت از آناستوموز و نقش هيپو آليومينمي و ساير عوامل با بروز آن در مبتلايان به سرطان مري و معده

Background: The role of preoperative dietary support in preventing cervical anastomatic leak in patients with esophageal cancer suffering from albumin level of <3.4gr/dl is controversial. Some studies have failed to reveal any association between malnutrition and anastomatic leak whereas the others had. Materials and methods: We have reviewed the reports of 421 patients underwent esophagectomy during a 12-year period, 1989-2001. Anastomatic leak was determined and the role of hypoalbuminemia and other related factors was judged. Results: Anastomatic leak was reported in 67 patients (15.9%). 16.2% of patients with hypoalbuminemia and 15.9% of non-hypoalbuminemic patients presented with anastomatic leak (NS). 80% of patients who lack blood supply to anastomatic edge had Anastomatic leak, however this was reported in 14.4% of patients who had blood supply (p<0.001). Conclusion: hypoalbuminemia had no correlation with anastomatic leak. Bear in mind the relatively high prevalence of Anastomatic leak (16%), further studies are suggested.