هدف: اي سلكتين بازگوكننده تخريب و فعالسازي اندوتليال ميباشد، همچنين نقش مهمي در فرايندهاي التهابي بازي ميكند. هدف از تحقيق حاضر بررسي تأثير هشت هفته تمرين مقاومتي تناوبي با شدت بالا بر سطح پلاسمايي اييسلكتين و شاخص هاي گلبولهاي سفيد در مردان سالم بود. روش شناسي: تعداد 23 نفر مرد جوان فعال از طريق فراخوان انتخاب و به روش تصادفي ساده به دو گروه تمرين مقاومتي تناوبي با شدت بالا (11 نفر) و گروه كنترل (12 نفر) تقسيم شدند. گروه تمرين به مدت 8 هفته فعاليت مقاومتي تناوبي با شدت بالا را به صورت 3 جلسه در هفته انجام داد و گروه كنترل زندگي عادي روزمره خود را ادامه داد. از آزمون t همبسته و مستقل در سطح 0/05 ≥P براي تحليل آماري دادهها استفاده شد.
يافتهها: يافته نشان داد كه 8 هفته تمرين مقاومتي تناوبي سبب كاهش معنيدار ايي-سلكتين شد (0/001 =P) اما بر منوسيتها، نوتروفيلها، آئوزينوفيل ها و لنفوسيت ها تأثير معني داري نداشت (0/05
چكيده لاتين :
Aim: E-selectin reflects endothelial degradation and activation, also plays an important role in inflammatory processes. The aim of this study was to investigate the effects of 8 weeks of high intensity interval resistance training on E-selectin and White blood cell indices in healthy men. Methods: twenty four active healthy men were selected and randomly divided into two groups: training (n=11) and control (n=12). Training group was performing high intensity interval resistance training for 8 weeks while control group continued their normal daily life styles. Dependent and independent t-test was used for statistically analyses of variances. Level of significance was p≤0.05. Results: the results showed that 8 weeks of interval resistance exercise decreased significantly level of E-selectin (p=0.001), but differences between control and training groups in monocytes, lymphocytes, basophiles and eosinophils was not significant (p>0.05), also there was significant relation between body weight and E-selectin changes (r=.67, p= 0.001). Conclusions: The results indicate that the high intensity interval resistance training did not result in white blood cells' indices excitation because of enough recovery between sets and repetitions, but E-Selectin were sensitive to exercise pressure and load imposed on body by training and showing higher adaptation to high intensity interval resistance training.