اثر خشكي دهان و هايپوساليويشن بر كيفيت زندگي بيماران دريافت كننده شيمي درماني

Effect of Xerostomia and Hyposalivation on Quality of Life in Patients Receiving Chemotherapy

هدف از اين مطالعه، تعيين اثر خشكي دهان و هايپوساليويشن بر كيفيت زندگي و ارزيابي ميزان جريان بزاق غيرتحريكي در بيماران دريافت كننده كموتراپي مي باشد. مواد و روش ها: مطالعه حاضر مطالعه اي توصيفي-تحليلي در ميان 80 بيمار مبتلا به سرطان و خشكي دهان تحت شيمي درماني مي باشد. براي بررسي اثر خشكي دهان و هايپوساليويشن بر كيفيت زندگي افراد از پرسشنامه OHIP-14 استفاده شد. يافته ها وارد نرم افزار SPSS 22 شد. يافته ها: اﻣﺘﯿﺎز 14-ADD-OHIP ﺑﺮاﺑﺮ 20/66 و 14-SC-OHIP ﺑﺮاﺑﺮ ﺑﺎ 3/10 ﺑﻪدﺳﺖ آﻣﺪ. از ﻣﺠﻤﻮع 80 ﺑﯿﻤــﺎر ﻣﺒــﺘﻼ ﺑــﻪ ﺧﺸﮑﯽ دﻫﺎن، 50 ﻧﻔﺮ ﻫﺎﯾﭙﻮﺳﺎﻟﯿﻮﯾﺸﻦ داﺷﺘﻨﺪ ﮐﻪ ارﺗﺒﺎﻃﯽ ﻣﻌﻨﯽدار ﺑﯿﻦ ﻫﺎﯾﭙﻮﺳﺎﻟﯿﻮﯾﺸﻦ و ﺧﺸﮑﯽ دﻫﺎن ﻣﺸﺎﻫﺪه ﺷﺪ )0/001

The aim of this study was to determine the effect of xerostomia and hyposalivation on quality of life in patients receiving chemotherapy and evaluating unstimulated salivary flow rate in these patients. Materials and methods: This descriptive-analytic study was conducted in 80 cancer patients with xerostomia undergoing chemotherapy. The Health Impact Profile-14 (OHIP-14) was administered to evaluate the effect of xerostomia and hyposalivation on patients’ quality of life. Data analysis was done in SPSS V22. Results: The additive and simple count OHIP-14 scores were 20.66 and 3.10, respectively. Among 80 patients with xerostomia, 50 had hyposalivation (P<0.001). Conclusion: Xerostomia and hyposalivation in patients undergoing chemotherapy have negative effects on oral health-related quality of life and these patients require more attention.