ﺑﯿﻤﺎري ﻣﻮﻟﺘﯿﭙﻞ اﺳﮑﺮوز ﺑﺮاﺳﺎس ﺣﺴﺎﺳﯿﺖ ﭘﺮدازش ﺣﺴﯽ ﺑـﺎ ﻣﯿـﺎﻧﺠﯿﮕﺮي ﮐـﺎرﮐﺮد اﺟﺮاﯾـﯽ ﺗﺼﻤﯿﻢﮔﯿﺮي ﻣﺨﺎﻃﺮهآﻣﯿﺰ

Modeling Multiple Sclerosis Based on Sensory Processing Sensitivity by Mediation of Risk Full Decision Making

زﻣﯿﻨﻪ و ﻫﺪف: ﻣﻮﻟﺘﯿﭙﻞ اﺳﮑﻠﺮوزﯾﺲ )MS( ﯾﮏ ﺑﯿﻤﺎري اﻟﺘﻬﺎﺑﯽ ﻣﺰﻣﻦ اﺳﺖ ﮐﻪ ﺑﺎ ﺿﺎﯾﻌﺎت دﻣﯿﻠﯿﻨﻪ در ﻣﻐﺰ، ﻃﻨﺎب ﻧﺨﺎﻋﯽ و ﻋﺼﺐ ﭼﺸﻤﯽ ﻣﺸﺨﺺ ﻣﯽﺷﻮد. ﻫﻨﮕﺎﻣﯽﮐﻪ ﻣﯿﻠﯿﻦ درﻧﺘﯿﺠﻪ ﺗﺸﮑﯿﻞ ﭘﻼك ﺗﺨﺮﯾﺐ ﻣﯽﺷﻮد، ﻫﺪاﯾﺖ ﻓﯿﺒﺮ ﻋﺼﺒﯽ ﮐﺎﻫﺶ ﻣﯽﯾﺎﺑﺪ و ﯾﺎ از ﺑﯿﻦ ﻣﯽرود. اﯾﻦ ﭘﺪﯾﺪه ﺳﺒﺐ ﻗﻄﻊ ﭘﯿﺎمﻫﺎي ﻋﺼﺒﯽ ﻓﺮﺳﺘﺎدهﺷﺪه از ﻣﻐﺰ و ﺑﺮوز ﻋﻼﺋﻢ ﺑﯿﻤﺎري ﻣﯽﮔﺮدد. اﯾﻦ ﺑﯿﻤﺎري ﻣﻨﺠﺮ ﺑﻪ اﺧﺘﻼل در ﮐﺎرﮐﺮدﻫﺎي ﺷﻨﺎﺧﺘﯽ ﻣﯽﺷﻮد. ﻫﺪف اﺻﻠﯽ اﯾﻦ ﭘﮋوﻫﺶ ﺑﺮرﺳﯽ راﺑﻄﻪ ﺣﺴﺎﺳﯿﺖ ﭘﺮدازش ﺣﺴﯽ ﺑﺮ ﻣﻮﻟﺘﯿﭙﻞ اﺳﮑﻠﺮروز ﺑﺎ ﻣﯿﺎﻧﺠﯿﮕﺮي ﮐﺎرﮐﺮد ﺗﺼﻤﯿﻢﮔﯿﺮي ﻣﺨﺎﻃﺮهآﻣﯿﺰ اﺳﺖ. ﻣﻮاد و روشﻫﺎ: روش ﭘﮋوﻫﺶ ﺗﻮﺻﯿﻔﯽ ﻫﻤﺒﺴﺘﮕﯽ از ﻧﻮع ﻣﺪلﯾﺎﺑﯽ ﻣﻌﺎدﻻت ﺳﺎﺧﺘﺎري اﺳﺖ. ﺟﺎﻣﻌﻪ آﻣﺎري ﭘـﮋوﻫﺶ ﮐﻠﯿـﻪ ﺑﯿﻤـﺎران ﻣﺒﺘﻼﺑـﻪ ﻣﻮﻟﺘﯿﭙـﻞ اﺳﮑﻠﺮوزﯾﺲ ﻣﺮاﺟﻌﻪﮐﻨﻨﺪه ﺑﻪ اﻧﺠﻤﻦ اماس اﯾﺮان ﺑﻮدﻧﺪ ﮐﻪ از ﻣﯿﺎن آنﻫﺎ 200 ﻧﻔﺮ ﺑﻪ روش ﻧﻤﻮﻧﻪﮔﯿﺮي ﻏﯿﺮ ﺗﺼـﺎدﻓﯽ در دﺳـﺘﺮس ﺑـﺎ ﻣـﻼك ﻫـﺎي ورود و ﺧﺮوج اﻧﺘﺨﺎب ﺷﺪﻧﺪ. در راﺳﺘﺎي ﺑﺮرﺳﯽ ﺳﻄﺢ ﺣﺴﺎﺳﯿﺖ ﭘﺮدازش ﺣﺴﯽ در ﺑﯿﻤﺎران از ﻣﻘﯿﺎسﻫﺎي ﺷﺨﺺ ﺑﺎ ﺣﺴﺎﺳﯿﺖ ﭘـﺮدازش ﺣﺴـ ﯽ ﺑـﺎﻻ آرون و آرون )1997( و ﺑﻪﻣﻨﻈﻮر ارزﯾﺎﺑﯽ ﺳﻄﺢ ﺗﺼﻤﯿﻢﮔﯿﺮي ﻣﺨﺎﻃﺮهآﻣﯿﺰ و ﺷﺪت ﺑﯿﻤﺎري ﻣﻮﻟﺘﯿﭙﻞ اﺳﮑﻠﺮوز در ﺑﯿﻤﺎران، ﺑـﻪ ﺗﺮﺗﯿـﺐ آزﻣـﻮن ﻗﻤـﺎر آﯾـ ﻮا ﺑﺸـﺎر ا، داﻣﺎﺳـﯿﻮ داﻣﺎﺳﯿﻮ، اﻧﺪرﺳﻮن )1994(، ﻣﻘﯿﺎس وﺿﻌﯿﺖ ﻧﺎﻧﻮاﻧﯽ ﮔﺴﺘﺮده ﮐﻮرﺗﺰﮐﻪ )1983( اﺳﺘﻔﺎده ﺷﺪ. ﯾﺎﻓﺘﻪﻫﺎ: ﺗﺤﻠﯿﻞ ﻫﻤﺒﺴﺘﮕﯽ ﻧﺸﺎن داد ﮐﻪ راﺑﻄﻪ ﻣﻌﻨﺎداري ﺑﯿﻦ ﺣﺴﺎﺳﯿﺖ ﭘﺮدازش ﺣﺴﯽ ﺑﺎ ﻣﻮﻟﺘﯿﭙﻞ اﺳﮑﻠﺮوز و ﮐﺎرﮐﺮد ﺗﺼﻤﯿﻢﮔﯿﺮي ﻣﺨﺎﻃﺮهآﻣﯿﺰ وﺟﻮد دارد. ﺑﺮاﺳﺎس ﻧﺘﺎﯾﺞ، ﺗﺄﺛﯿﺮ ﺣﺴﺎﺳﯿﺖ ﭘﺮدازش ﺣﺴﯽ ﺑﺮ ﻣﻮﻟﺘﯿﭙﻞ اﺳﮑﻠﺮوزﯾﺲ ﺑﻪواﺳﻄﻪ ﮔﺮي ﺗﺼﻤﯿﻢﮔﯿﺮي ﻣﺨﺎﻃﺮهآﻣﯿﺰ ﺗﻌﺪﯾﻞ ﯾﺎﻓﺖ )0/001

Aim and Background: Multiple sclerosis (MS) is a chronic inflammatory disease characterized by demyelinated lesions in the brain, spinal cord, and optic nerve. When myelin is destroyed by plaque formation, nerve fiber conduction is reduced or lost. This phenomenon interrupts the nerve messages sent from the brain and causes the symptoms of the disease. This disease leads to dysfunction of cognitive functions. The main purpose of this study was to investigate the relationship between sensory processing sensitivity on multiple sclerosis mediated by risk decision making function. Methods and Materials: The research method is descriptive correlation of structural equation management. The statistical population of the study was all patients with multiple sclerosis referred to the Iranian MS Association, from which 200 people were selected by non-random sampling method with inclusion and exclusion criteria. In order to evaluate the level of sensory processing sensitivity in patients from personal scales with high sensory processing sensitivity, Aaron and Aron (1997) and in order to assess the level of risky decision making and severity of multiple sclerosis in patients, respectively used the IOWA gambling test Damasio, Bashara, Damasio, Anderson (1994), Extensive Disability Status Scale Kurtzke (1983). Findings: The analysis showed that there were significant correlations between and sensory processing sensitivity with multiple sclerosis and risk full decision making. According to the results of the mediation؛ the effect of sensory processing sensitivity on the multiple sclerosis, was moderated by the risk full decision making (p>0.001). Conclusions: As a result of structural equation sensory processing sensitivity risk full decision making, and multiple sclerosis according to indicators of fitness is good.