مقايسه اثر بي دردي تزريق داخل مفصلي ژل هيالورونيك اسيد در بيماران دچار آرتروز زانو پيش و پس از تزريق در بيمارستان امير اعلم تهران

Comparison of the analgesic effect before and after injection of hyaluronic acid in patients with knee osteoarthritis in Amir A'alam hospital

يكي از مهمترين مسايل مربوط به بيماران مبتلا به استيوآرتريت كاهش درد و بازگرداندن آن ها به زندگي طبيعي است. براي كنترل درد ممكن است درمان هايي لازم باشد. از جمله اين درمان ها تزريق ژل هيالورونيك اسيد به مفصل زانو مي باشد. روش بررسي در اين مطالعه تحليلي كه از آذر 1398 تا ارديبهشت 1400 در بيمارستان امير اعلم انجام شد، تعداد 61 نفر از افراد دچار آرتروز زانو وارد مطالعه شدند و شدت درد، دامنه حركتي مفصل زانو و التهاب مفصل در آن ها سنجيده شد. سپس در آن ها تزريق ژل هيالورونيك اسيد صورت گرفت و پس از تزريق مجددا اين متغيرها مورد سنجش قرار گرفت. ﯽ ﺑﯿﻤﺎران در اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺑﺮاﺑﺮ ﺑﺎ 60/52±11/77 ﺳﺎل ﺑﻮد. ﺷﺎﺧﺺ درد ﭘﯿﺶ از ﺗﺰرﯾﻖ در ﺑﯿﻤﺎران ﺑﺮاﺑﺮ ﺑﺎ 7/90±0/99 ﺑﻮد ﮐﻪ در روز ﺳﻮم ﺑﻪ 5/49±1/91، در روز ﻫﻔﺘﻢ ﺑﻪ 5/28±1/98 و در روز ﺳﯽام ﺑﻪ 3/77±2/91 ﮐﺎﻫﺶ ﯾﺎﻓﺖ )0/001

One of the most important issues for patients with osteoarthritis is reducing pain and returning them to normal life. In addition to losing weight and improving daily activities, pain management treatments may be needed. One of these treatments is the injection of hyaluronic acid gel into the knee joint, which has been studied in this study. Methods In this study, 61 patients with knee osteoarthritis were included and the Then, they received the injection of hyaluronic acid gel, and the intensity of pain, range of motion of the knee joint, and inflammation of the knee joint were measured. The numeric rating scale was used to measure pain intensity, and movement angle was used to measure the range of motion Results The mean age of patients in this study was 60.52±11.77 years. Pre-injection pain index in patients was 7.90±0.99, which decreased to 5.49±1.91 on the third day, 5.98±1.98 on the seventh day and 3.77±2.91 on the 30th day (P<0.001). The amplitude of painless movement based on the degree before injection in patients was 38.85±19.44 which increased to 60.25±21.65 on the third day to 65.25±22.65 on the seventh day and to 71.07±24.17 on the 30th day (P<0.001). Inflammation rate was reported before injection in 29 patients which decreased to 6 patients on the third day after injection (P=0.009). Conclusion Injection of hyaluronic acid into the joint has analgesic effects and significantly improves the function and range of motion of patients. It is recommended that hyaluronic acid could be considered as a suitable drug in the treatment process of these patients. Considering that using this method, which is a useful treatment method in reducing patients' pain and improving their function, we recommend this method, especially in the elderly and without the need for surgery.