تاثير هشت هفته تمرين تركيبي بر سطوح پلاسمايي رزيستين و آديپونكيتن در مردان ميانسال

The Effect of Eight Weeks of Combined Rehabilitation Training on Plasma Levels of Resistin and Adiponectin in Middle-Aged Men after Coronary Artery Bypass Grafting

سابقه و هدف : بيماري هاي قلبي عروقي يكي از علل اصلي مرگ­ مير در جهان ­است. هدف ازپژوهش حاضرتاثيرهشت هفته تمرين تركيبي برسطوح آديپونكتين ورزيستين درمردان ميانسال پس ازانجام عمل باي­پس عروق­ كرونري بود. روش بررسي: روش پژوهش­ حاضرنيمه ­تجربي و باطرح پيش­ آزمون، پس ­آزمون بود. جامعه آماري­ كليه بيماران باي­پس عروق­ كرونري شهرمشهد بودند. در مطالعه حاضرنمونه پژوهشي شامل 26 مرد ميانسال پس ازعمل باي­پس عروق كرونرتشكيل دادندكه براساس معيارهاي ورودبه تحقيق، در2گروه درتجربي (14) وكنترل (12) قرارگرفتند. داده­ ها با استفاده از آزمون ت ­زوجي وتي­ همبسته در­سطح معني­ داري 05/0≥P تجزيه و تحليل شد. يافته ها: نتايج آزمون آماري تي همبسته نشان­ داد سطوح آديپونكتين درگروه تمرين ­تركيبي به ­دنبال هشت هفته تمرين تركيبي به طورمعني داري افزايش يافت(0/001=P)، اما درگروه كنترل كاهش غيرمعني داري داشت (0/577=P). همچنين نتايج آزمون تي­ مستقل نشان داد سطوح آديپونكتين گروه تمرين­ تركيبي به طور معني داري نسبت به گروه كنترل بالاتر بود(0/0001=P). همچنين دررابطه با شاخص رزيستين، نتايج آزمون تي­ همبسته نشان داد سطوح اين شاخص درگروه تمرين تركيبي پس از هشت هفته اجراي پروتكل تمرين به طور معني داري كاهش يافت (0/005=P). اما درگروه كنترل افزايش غيرمعني داري مشاهده شد (0/720=P). همچنين نتايج آزمون تي ­مستقل نشان داد سطوح رزيستين گروه ­تمرين­ تركيبي به طور معني داري نسبت به گروه كنترل كاهش داشت(0/0006=P).

Background and Objectives: Cardiovascular diseases are one of the leading causes of death in the world. The aim of the present study was to evaluate the effect of eight weeks of combined exercise on adiponectin and resistin levels in middle-aged men after coronary artery bypass grafting. Method and Materials: The research method was quasi-experimental and pre-test with post-test. The statistical population was all patients with coronary artery bypass grafting in Mashhad. In the present study, a research sample consisting of 26 middle-aged men after coronary artery bypass graft surgery was divided into experimental (14) and control (12) groups according to the inclusion criteria. Data were analyzed using paired t-test and correlated t-test at the significance level of P≥0.05. Results: The results of paired t-test showed that adiponectin levels in the combination group increased significantly after eight weeks of combination training (P = 0.001), but decreased significantly in the control group (P = 0.577). Also, the results of independent t-test showed that adiponectin levels in the combined exercise group were significantly higher than the control group (P = 0.0001). Also, in relation to the resistin index, the results of the correlation test showed that the levels of this index in the combined training group decreased significantly after eight weeks of training protocol (P = 0.005). But in the control group, a non-significant increase was observed (P = 0.720). Also, the results of independent test showed that the resistance levels of the combined exercise group were significantly reduced compared to the control group (P = 0.006) Conclusion: The present study showed that combination exercises because positive changes in cardiovascular factors and can be used as a non-pharmacological method to treat these diseases.