نقش ويروس سرخجه در بيماران مبتلا به عفونتهاي حاد بثوري در مناطق مختلف كشور

Role of rubella in patients with acute febrile rash in different parts of Iran

In this study we have tried to evaluate the frequency of acute rubella infection in patients with acute exanthematous disease occuring in different geographical areas of Iran. For this purpose, laboratory investigation for detection of acute rubella infection has been performed on serum samples of 1169 patients surveyed in the context of Measles Elimination Programme, in which acute measles was excluded by laboratory testing. Serological diagnosis of acute rubella has been perfarmed by demonstration of seroconversion or antibody rise in hemagglutination inhibition test or by detection of IgM in Capture IgMEIA. Acute rubella infection has been detected in 51.8% of all 1169 measles negative cases and this rate was 63.6, 61 and 29.7 percent far north, central and south part of Iran, respectively. 1169 measles negative cases corresponded to a total of 2728, febrile rash patients, relative. ferquency of acute rubella in these patients was 22.2% and this rate was 37%, 24.9% and 10.5% for north, central and south part of Iran, respectively. Relative fequency of acute rubella in exanthematous patients was 31.1% in patients below 15 years old compared to 7.4% in those equal and older than 15 years old.