بررسي ارتباط بين گروه خوني و ميزان انتوباسيون و مورتاليتي در بيماران 19-COVID

Evaluation of the relationship between blood group and intubation and mortality rate in covid 19 patients

كرونا ويروس (COVID-19) نشان دهنده يك بحران بهداشت عمومي در ابعاد جهاني است كه باعث مرگ و مير قابل توجه مي شود. عوامل خطر متعددي براي شدت عفونت، عوارض و مرگ و مير COVID-19 وجوددارد. كه يكي از آن ها گروه خوني است هدف از اين مطالعه بررسي ارتباط بين گروه خون و ابتلاي به كوويد 19 بود. روش بررسي مطالعه اي مقطعي برروي 130 بيمار بستري در ICU بيمارستان شهداي تجريش از تاريخ شهريور ماه 1399 تا فروردين ماه 1400 صورت گرفت. تشخيص بيماران COVID-19 مثبت توسط آزمون واكنش زنجيره اي پلي مراز (PCR)، تاييد گرديد. گروه خوني آن ها، تعيين شد و سپس outcome بيماران را طي مدت زمان بستري از نظر بستري در ICU، follow كرديم. داده ها با استفاده از پرسشنامه جمع آوري و با استفاده از محاسبه Pearson correlation coefficient و تحليل رگرسيون چندگانه گام به گام (stepwise multiple regression analysis)، تحليل شد. نتايج براساس Fisher’s exact test مشخص گرديد.05/0

Coronavirus (COVID-19) represents a global public health crisis that is causing significant deaths and affecting health systems around the world. There are several risk factors for the severity of infection, complications and mortality of COVID-19. One of them is blood group. The aim of this study was to investigate the relationship between blood group and rate of covid 19 disease. Methods: A cross sectional study was performed on 130 patients over 18 years of age admitted in ICU of Shohada Tajrish Hospital between August 2020 and April 2021.The positive COVID-19 diagnosis was confirmed by polymerase chain reaction (PCR) test. Blood groups were determined and then, we monitored and followed up the patients' outcome during staying in ICU, the need for intubation, recovery and death. Data were collected using a questionnaire and analyzed by Pearson correlation coefficient and stepwise multiple regression analysis. Results were determined based on Fisher’s exact test. P<0.05 was considered significant. Results: 60 (46.1%) patients had blood type A, (20%) 26 patients blood type AB, 12 (9.2%) patients’ blood type B and (24.7%) 32 patients blood type O. Blood group A was significantly higher in these patients. 55 patients (42.3%) were female and 75 patients (57.7%) were male. Their mean age was 43.19±19.05. Totally, 43.1% of hospitalized patients were intubated regardless of blood type. The number of cases requiring intubation was higher in people with positive blood type A. The lowest need for intubation was seen in blood type B negative. Blood group A positive (39.6%) and then AB negative (33.3%) had the highest mortality rate. Death was not observed in blood group A negative, B negative, B positive and O negative. Conclusion: The number of patients with COVID-19 with blood type A was significantly higher (46.1%). The most common blood group in these patients was A and the lowest was blood group B. The number of cases requiring intubation was higher in people with positive blood type A.