كليدواژه :
Islamic fasting , CAD risk factors , روزه داري , هيپركلسترومي , بيماريهاي عروق كرونر , پزشكي , Primary Prevention
چكيده لاتين :
Coronary Artery Disease (CAD) is the leading cause of mortality in industerialized and many of developing countries. Incidence of CAD in groups with risk factors is relatively high. This prospective study was done on 120 volunteers (84 male and 36 Female) with mean age of 31.8 yr (14-67 yr old) with at yleast 20 days of fasting during the holy month of Ramazan from Dec. 1998- Jan. 1999. Main goal of this study was to evaluate the effect of Islamic fasting on blood biochemistry, weight, BMI, and systemic arterial blood pressure. The correlation of the above values with age, sex, BMI and number of days of fasting were studied. Islamic fasting with at least 20 days caused significant reducion in total cholestrol (4.6mg/dl, PV=O), LDL-C (5.98 mg/dl, PV=0.002), TG (10.42 mg/dl, PV=0) and weight (2.3kg PV=O), BMI (0.79 kg/m2, PV=0) and number of cigaret per day (PV=O, N=8.5). It had no significant effect on systolic and diastolic blood pressure and HDL - C. Also, significant increase in FBS (4.2mg.u1, PV=0.001) was detected. There was no significant correlation between serum lipids and systolic and diastolic blood pressure with age or sex or BM1 or even number of fasting more than 20 days. However, the increase in level of FBS had significant correlation with age. Therefore, Islamic fasting is useful and cost effective method for risk factor modification in normal subjects which may reduce CAD.
