بررسي شيوع تالاسمي مينور در داوطلبين ازدواج استان كرمان

DETERMINATION OF THE RATE OF INCIDENCE OF THALASSEMIA MINOR AMONG MARRIAGE CONDIDATES IN KERMAN

Thalassemia is a disease that is congenitally transmitted from the parents with diseased genes to their descendants and affects an important percentage of the children in certain parts of the world. It leads to an anemia due to a defect in production of one or chains certain of hemoglobin. Depending on the type of defect , thalassemia has been divided into two types : Alpha and Beta. Transmitter of the defective genes of minor thalassemia have quite healthy apearances these defective cases in fathers or mothers can be realized only through blood testing. Thalassemia has been known as an endemic and local disease incertain areas . Kerman is one of those ten provinces in the country in which thalassemia is widely endemic . In order to determine the vate of incidence of thalassemia minor in Kerman , the recent research was carried out among the marriage candidates Tir 1377-1378. This sectional descriptive study whose purpose was to determine the rate of incidence of the disease among the marriage candidatestir carried out in Kerman between 77 and 78. The total number of samples studied was 27946 of which 1606 (5.7%) were thalassemia minors (829 men & 777 women) . The percentage of affected individuals varied greatly according to the geographical location (31.3% to 2%) . Results did not show a significant relation between disease and gender , but it is noteworthy that educational qualifications as compared to family and vesidential location had a significant relationship with the diseaae (P<0.001). A very important finding was that of the 110 couples who were carriers of thalassemia , only 7 decided to part ways , and this points out to the high level of unawareness among the general population which is responsible for increase in the number of thalassemia magor cases in our society . Therefore , all the responsible authorities and mass communication instruments , especially those which can reach the rural areas should seriously chalk out strategies and plans in order to increase the general awareness and decrease the rate of incidence of thalassemia major in our country .