مقايسه اثر فنيل افرين مخاطي با افدرين داخل وريدي در پيشگيري و درمان افت فشارخون ناشي از بي حسي داخل نخاعي

A COMPARISON OF THE EFFCETS OF SUBLINGUAL PHENYLEPHRINE AND PARENTERAL EPHEDRINE IN PROPHYLAXIS AND TREATMENT OF HYPOTENSION DUE TO SPINAL ANESTHESIA

The aim of this study Was to compare the antihypotensive effects of sublingual phenylephrine and parenteral after spinal anesthesia. 120 patient who needed spinal anesthesia were selected.In 60 patients , 2mg of sublingul phenylephrine and in others, 2mg parenteral ephedrine was used before anesthesia. Systolic and diastolic blood pressure, MAP, heart rate and 02 Saturation were compared. The mean systolic blood presure in the phenylephrine group ( groupl) was 120.3 ± 6.5 mmHg and 119.2 ± 6.7mm/Hg in the ephedrime group (P-0.97) . The mean diastolic blood pressure in group I was 74 ± 14.39mmIHg and 69.1 ± 5.9mmlHg in group II (P-0.21) . MAP in group I was 104.5 ± 6.4 mm/Hg and 102.4 ± 5.6 mm/Hg in group II ( P=0.82) . The mean heart rate in the two groups were 74.07 ± 4.9 and 79.3 ± 4.7 perminute respectively (P=0.9) . Our findings suggest that sublingual phenylephrine can be used to prevent hypotension due to spinal anesthesia.