بررسي اثر مصرف مكمل آهن بر عواقب بارداري زنان باردار با هموگلوبين بيش از 13/2 گرم در دسي ليتر

Consideration of Iron Supplementation Effects on Pregnancy Outcomes in Women with Hemoglobin Higher Than 13/2 gram/dl

Introduction: Although there are numerous evidences which show that consumption of iron, as supplementary has element remarkable positive effects on iron status in pregnant women at their delivery, and later hemoglobin with increased risk of small embryo gestational age, still birth, pregnancy induced hypertension, intrauterine restriction, low birth weight, preterm birth, and prenatal death. In these cases, it seems that normal blood volume has been decreased in pregnancy. Material & Methods: 193 pregnant women with hemoglobin concentration higher than 13.2 gr/dl in 13th and 18th weeks of pregnancy participated in a randomized double blind placebo-controlled trial. One hundred and twenty two women were given one ferrous sulfate pill containing 50 mg iron, daily from 20th week of pregnancy up to the end of it and 71 pregnant women were given one placebo daily during the same period. In order lo control the procedure for hemoglobin changes, all women took blood tests in the 24th - 28ʹh and 32nd - 36th weeks of pregnancy, If their hemoglobin concentration decreased less than 10.5gr/dl in the first trimester and less than 11 gr/dl in the third trimester, they were excluded from the study for the iron treatment. Results: The results of this study revealed that routine consumption of iron supplementation by pregnant women from second half of pregnancy with hemoglobin concentration higher than 13.2 grldl in 13th - 18 weeks of pregnancy in comparison with pregnant women who have not received iron supplementation significantly increases low birth weight frequency (less than 2.5kg). But, there was no significant difference between two groups in duration of pregnancy, pre-term delivery, and type of delivery. Conclusion: In sum, it seems that consumption of iron supplementation by pregnant women whose hemoglobin concentration is higher than 1312gr/dl in the second trimester may slow down the reduction of hemoglobin, hematocrite, and ferritin levels during pregnancy, which exposes them to the increased risk of low birth weight because of lack of suitable blood hemodilusion and ultimately damages utero-placental circulation.