توليد انسولين به وسيله سلول هاي بنيادي انسان

Insulin Production by Human Stem Cells

Diabetes Mellitus is the most common endocrine disorder. Life-long assessments of blood sugar, daily insulin injections and limited nutrition regimes constantly disrupt and disturb the diabetic patientʹs daily life. On the other hand, treatment of diabetes complications are a major burden on the national health budget. In the last decade, pancreas islet transplantation has been developed as a potential treatment of diabetes; however, shortage of donor organs is a major problem. Stem cells are a reproducible source of cells and can be differentiated into different organs or cells. Stem cells have been proposed as a potential treatment of diabetes. Animal studies, embryonic stem cells, human stem cells derived from the hematopoetic system, liver and pancreas have been used for this approach. This paper reviews different studies in this field.