كليدواژه :
پزشكي , آزمايش مرفين , كنترل كيفي , ادرار , External Quality , Assessment Scheme.
چكيده لاتين :
Introduction: Addiction to opium and morphine can be studied from different angles including personal, social, psychic, and etc. In addiction studies the important part is the accuracy and precision of morphine identification in urine tests. Reporting any incorrect results will Cause major problems to the patients as well their family members. The aim of the present study was to evaluate the morphine identification methods in urine used in the laboratories country-wide.
Materials and Methods: In the first trial (Feb 2002) of morphine identification External Qualiy Assessment Scheme (EQAS), more than 900 urine lyophilized unknown samples were prepared and distributed among 300 morphine identification laboratories across the country. Three samples including; negative, positive, and false positive were sent to the each laboratory. The testing procedure for reporting the correct result, arranged in a way that a technologist analyzed the sample in two steps, first by using screening methods identified the negative sample and then by using chromatography methods confirmed the positive and false positive samples.
Results: Obtained results indicated that 36% of engaged laboratories in the study, reported test results without any further confirmation. About 29% of the laboratories that used confirmatory tests and about 80% of them that used screening methods reported false results.
Discussion: With respect to the initial results, it was obvious that urine morphine identification laboratories need more supervision. In addition, Methodʹs accuracy, precision, and sensitivity should be checked and assures. Sine reporting any incorrect result may cause problems for the individual and even his family, subsequent control regarding routine methodʹs accuracy for morphine identification is necessary. Moreover, introducing standard methods in this matter can be of help.
