PRECURSORT CELL گزارش يك مورد نادر پاسخ دهي مياستني گراو به درمان لمفوم لمفوبلاستيك

RESPONSE OF MYASTHENIA GRAVIS TO THE TREATMENT OF PRECURSOR-T-CELL LYMPHOBLASTIC LYMPHOMA : REPORT OF A RARE CASE

Background & Aim : The aim of this study is to determine an association between lymphoblastic lymphoma and myasthenia gravis. A 23-year-old male patient with myasthenia gravis (MG) developed mediastinal precursor T-lymphoblastic lymphoma (LBL), 15 months after MG diagnosis and treatment, presented with classic symptoms and MG crisis as a sign of LBL. LBL subtype was determined by using an immunohistochemistry test for B or T cell differentiation. His LBL did not show any high risk factors. His reaction was very well to CHOP (Cyclophovphamide, Doxorubicin, Vincristine, Prednisolone) chemotherapy with significant reduction in his myasthenic symptoms. Discussion: Decrease in signs of disease can show a significant relation-ship between myasthenia gravis and mediastinal lymphoblastic lymphoma.