در اسكن استخوان بيمار دياليزي مبتلا به آميلوييدوز (گزارش موردي ) TC-99M MDP جذب قلبي

Myocardial 99mTc-MDP Uptake on the Bone Scintigraphy In the Hemodlalysis -Assoclated Amyloldosis: A Case Report

Amyloidosis is characterized by an abnormal extracellular deposition of amyloid in different organs, where it usually causes some type of dysfunction. Its cause is unknown. Five different types of amvloidosis have been described according to the underlying disease: immunoglobulin amyloidosis, familial amyloidosis, senile systemic amyloidosis, secondary amyloidosis and hemodialysisassociated amyloidosis. We report a case of hemodialysis-associated amyloidosis in a 56-year-old man that radionuclide imaging demonstrated intense uptake of Tc-99m MDP within the myocardium. The diagnosis of amyloidosis was established by analysis of aspirated abdominal fat, although other non- invasive modalities didn ʹt reveal any positive findings. The first clue to the possible presence of amyloidosis in this case was provided by the radionuclide bane scan performed, which revealed intense tracer uptake in the heart suggesting amyloid deposit. We conclude that in cases of extraosseous accumulation of re-99 MDP especially as a diffuse pattern of myocardial uptake, a diagnosis of amyloidosis should be considered, in an appropriate clinical setting.