پايش شيوع گواتر و ميزان يد ادرار در دانش آموزان 8 تا 10 ساله استان خراسان در سال 1375

Goiter survey and urinary iodine concentration in schoolchildren aged 8 to 10 years

Iodine Deficiency Disorders (IDD) is a worldwide health problem. Many parts of the Islamic Republic of Iran had been known as areas of endemic goiter. IDD was accepted as a priority health problem in the country, and a National IDD council was formed in 1989. One of the main strategies of National council for IDD control was to provide at least 150 |LLg of iodine per day to the entire population through making available iodized salt. This study was performed to evaluate the National IDD council program in 1996, in rural and urban areas of Khorasan province. 1400 schoolchildren, aged 8 to 10 year, including 50% girls and 50% boy, were selected through random sampling. Grading of goiter was performed according to WHOʹs classification. RIA and urinary iodine measured serum T3 ,T4 and TSH by digestion method. The mean of serum T4, T3 and TSH were: 10.0 ± 2.0 |Ug/dl, 162±122 ng/dl and 1.8±2.0 \i\\xl ml, respectively. There was no difference between males and females and schoolchildren of rural or urban areas. Two people had serum T4 more than 12.5 (ig/dl and seven people had TSH more than 5 (xlu/ml. The mean urinary iodine was 25 jLLg/dl in entire population, 90% had urinary iodine more than 10 |Lig/dl. Only 4% had urinary iodine less than 5 |Lig/dl. Total prevalence of goiter was 41 % (46% in girls and 43% in boys). Based on the available data, seven years after generalized use of iodized salt and 2 years after more than 50% of population used iodized salt, urinary iodine of schoolchildren in Khorasan province showed sufficient intake of iodine. However, goiter is still endemic in Khorasan province.