اختلالات قلبي در بتاتالاسمي ماژور

Cardiac complications in Beta-Thalassemia Major

Quality and life span of thalassemia patients dependent on blood transfusion has been changed during recent years. But early death due to cardiovascular problems is still important. The most important reasons for mortality and -morbidity are cardiac complications. This research, randomized on 78 patients with Beta-Thalassemia, cases were selected from patients who were referred to hematology clinic of Dr. Sheikh Hospital in Mashhad University as out patients. There were significant differences between blood transfusion times and left ventricular feeling period (LVFP) [P=0.026] and its ratio to left ventricular emptying period (P=0.050), between serum ferittin and PR interval on EKG (P=0.000). In other evaluations there was no significant deference. LV end-diastolic, end-systolic, interventricular septum and posterior wall diameters was upper than 75 percentiles, which could be because of their chronic anemia. None of the patients had overt heart failure.