بررسي اپيدميولوژيك و آسيب شناسي بازال سل كارسينوما

Epidemiologic and pathologic study of Basal cell carcinoma (BCC)

Introduction: BCC (basal cell carcinoma) is the most common malignant neoplasm of the skin.Ultra-violet ray is the most important risk factor for it. The purpose of this study is to investigate the epidemiologic features and the effect of diverse variables on each other. Material and Methods: This descriptive study from 1982 to 2002 was done in skin and pathology department of Mashhad Imam Reza hospital. 1844 patients with BCC are evaluated. Patients information including age, sex, localization and job was collected in forms. Collected data were processed by descriptive statistics, frequency tables and analytical statistics. Results:l844 BCC cases with an age range (mean ± 2SD) of 58±28 years and a man to women ratio of about 1.46 to 1 were found. which shows a meaningful difference (p<0.001) between the mean age of men (60 years) and women (55 year) .The most prevalent site of involvement are nose, face, per orbital and scalp regions respectively.%85 of patients are in age range of 40 to 79 years. Children (less than 15 years) constitute only %0/23 of cases. It seems that in both sex by increasing the age there is a reduction in the relative prevalence of BCC in scalp and ear regions and an increment in lip and nose areas. Women have a meaningful (p<0.001) lower relative prevalence in ear and neck sites. Also in this study chest, shoulder, and back (non sun-exposed areas) constitute only about %1 of all BCC cases which shows a great difference with other references(about %15). A clear correlation was not found between job and involved region of the skin. Conclution: Higher prevalence of BCC and higher rate of scalp and ear skin involvement in men may be due to occupational factors and special style of clothing in women. Much less relative involvement of non-sun exposed areas both in men and women may also be a reflection of social habits and daily clothing style.