بررسي ميزان شيوع باكتريمي و تعيين ارگانيسم هاي شايع پس از تعويض خون در نوزادان بستري در بيمارستان شهيد اكبرآبادي طي سال هاي 1378-1375

THE PREVALENCE OF BACTEREMIA AND DETERMINATION OF THE MOST COMMON ORGANISM AFTER EXCHANGE TRANSFUSION IN NEWBORNS IN AKBAR ABADI HOSPITAL (1996-1999)

Jaundice is one of the most complications in the neonatal period. Bilirubin encephalopathy (kernicterus) is one of the important complications of indirect hyperbilirubinemia, that causes extrapyramidal, audiotory and visual disturbance. To prevent of this dangerous complication can used from three manner treatment including: phototherapy, exchange transfusion and drug. Exchange transfusion is done from the umblical vein catheterization. The purpose of this study was to evaluate the prevalence of bactremia which is one of the complications of exachange transfusion. This study designed prospectively and conducted on the infants who where hospitalized with jaundice between 1996-1999 in shahid Akbar Abadi hospital and underwent exchange transfusion. Blood culture was done before and after exchange transfusion (ET) and also the most common responsible organism that causes bacteremia after transfusion was recognized. In this study, the pre-term infants (less than 37 weeks) and neonates who had clinical manifestation of sepsis and so infants who had more than one exchange transfusion were omitted. Of 402 hospitalized infants, who possessed the qualifications in this 4 years, 40 infants (9.95%) underwent exchange transfusion (19 infants were female and 21 infants were male). Of these 40 infants, in 29 infants (67.5%) blood cultures (before and after ET) were negative. In 13 infants (32.5%) blood culture was positive; in 4 of them (10%) before ET, and in 9 of them (22.5%) after FT. The most common micro organism in positive blood cultures after ET, was coagulase positive staphylococcus (66.5%). Based of this study, the rate of bacteremia after ET was 22.5% which is higher than other countries (8-10 percent). The most common responsible micro organism of bacteremia after FT as the same as other researches was coagulase positive staphylococcus.