بروز ساركوم كاپوسي به دنبال درمان سركوب گر ايمني در بولوز پمفيگوييد:معرفي 1بيمار

Kaposiʹs Sarcoma after Immunosuppressive Terapy for Bullous Pemphigoid: A Case Report

Kaposiʹs sarcoma is a malignant neoplasm of lymphatic and blood vessels endothelial cells. The disease is classified into four clinical subtypes, all of which are associated with human herpes virus 8(HHV-8). We report a 71-year-old man who was treated for six months with prednisolone and azathioprine for bullous pemphigoid and presented with multiple purple papules and plaques on ear, nose and fingers. Pathology of the lesions revealed Kaposiʹs sarcoma. Subsequently, the dose of azathioprine was lowered. There are few reported cases of Kaposiʹs sarcoma after immunosuppressive therapy for bullous pemphigoid and in some of these cases the pathogenic role of HHV-8 has been documented.