كليدواژه :
بافت چربي , اتوپسي اجساد ارجاعي , Residues , Chlorinated organic pesticides , Fat tissue , آفت كشهاي آلي كلره , پزشكي
چكيده لاتين :
Background: Dichlorodiphenyltrichloroethane (DDT) was introduced as a pesticide in the late 1930s. After then other organic chlorinated pesticides were introduced to the market. The remnants of these compounds have been found in air, water, food and bodies of human and animals and biological-environmental consequences has been ascribed to them. With regard to the long term toxic effects of these toxins and their accumulation in fat tissues, we measured organic pesticide remnants in corpses referred to Tehran Legal Medicine Organization in summer and fall 1380.
Methods: Random specimens were collected from abdominal fat of corpses. Gas layer chromatography was used to determine concentrations of eight major organic chlorinated compounds (lindane, dieldrin, alphaendosulfan, beta-endosulfan, OPʹ DDT, PPʹ DDT, PPʹ-DDE, PPʹ DDD). Extraction was done by liquid in liquid extraction by organic solvents using decanter funnels. Thin layer chromatography was used for screening, and confirmation of the method of reporting measures was performed by gas layer chromatography.
Results: Analysis of 64 samples (32 male, 32 female) revealed the following results:. 26 samples contained lindane, 59 had dieldrin, I0 had alphaendosulfan, 10 had beta-endosulfan, 4 disclosed OPʹ DDT, 3 revealed PPʹ DDT in them, 7 had PPʹ DDE, and at last 2 samples showed some measures of PP DDD.
Conclusion: The results clearly show that all samples contained one or more of the investigated toxins. Concentration of dieldrin in 60 years old people was significantly higher than younger ages. No relationship was found between sex and toxins concentrations in fat tissues.
