و فراواني افراد ايمن نسبت به سرخجه در دختران 14-18 ساله شهر رفسنجان در سال 9731 IGG بررسي سطح آنتي بادي

Determination of Seroprotection Rate Againts Rubella Virus in 14-18 Year Old Girls in Rafsanjan City in the Year 2000

Background: Congenital Rubella Syndrome (CRS) could be prevented if young women were aware of their immune status before pregnancy. This will decrease the congenital morbidity rate due to CRS among the children. Materials and Methods: To determine the level of antibody againts immunity to rubella in Rafsanjan city, 270 seras of 14-18 year old girls were evaluated retrospectively. ELISA method was used for detection of IgG antibody against rubella virus. Results: From 270 cases that participated in this study, 19 cases (7.1%) were nonimmune and 251 cases (92.9%) were immune according to this method. None of the individulas in this study had the history of rubella vaccination. The average of antibody concentration in groups of 14, 15, 16, 17 and 18 year olds were 264.8, 209.25, 241.25, 214.13 and 148.17 (Iu/ml) respectively. The amount of antibody decreases with age in all groups with some Exceptions. Conclusion: In order to prevent the congenital rubella syndrome, the immunity to virus in premarraige girls should be determined, and in case of low immunity vaccination should be recommended.