سرمي در زنان باردار تهراني A و E با ويتامين D بررسي رابطه كلسيم و ويتامين

The relationship between calcium & vitamin D and vitamins A and E in pregnant Tehranian women

Introduction: in recent years, increasing attention is being given to investigating the association between body levels of antioxidant vitamins and the prevention of disease. This study aims at evaluating the relationship between the status of serum calcium & vitamin D and vitamins A & E among Tehranian women. Materials & Methods: This was a cross sectional study in which 52 healthy pregnant women in their first trimester (less than 14 weeks) from 5 prenatal care centers, were assessed for their levels of serum calcium, vitamin D and vitamins A and E. Women using photo protection and calcium and vitamin D supplementation were excluded. Questionnaires were used to obtain demographic information and venous blood samples were taken after 12-14h of overnight fasting to measure serum calcium, vitamin D and serum levels of vitamins A & E. Pregnant women were divided to three groups; severely deficient (serum vitamin D Ievels25nmol/l). Serum levels of vitamin A, vitamin E and calcium were compared in these groups. A linear regression model and Post hoc test was used in the analysis of data. Results: Mean values of vitamin A and vitamin E in the severely vitamin D deficient, the moderate, and the normal vitamin D subjects were 1. 78±0. 4 and 1.0±0.5, 1.1±0.5 nmolll and 14.2±5.0, and 17.9±4.7 and 14.7±6.0 moll!, respectively Serum calcium levels were 9.0#0.6,9.3±0.6 and 9.2±0.6 mg/dL respectively. Serum vitamin A level was significantly higher in the severely deficient group (p<0.001). There was significant linear regression between serum calcium level and vitamin A (r=0.37, p<0.01). Conclusion: Serum levels of vitamin A were significantly higher in the severely deficient group as compared to those moderately deficient and the normal group.