بررسي برخي عوامل خطر سرطان پستان در زنان بالاي 35 سال شيراز 1380

Background: Breast cancer is the most prevalent cancer among women throughout the world that can be treated easily in case of early diagnosis. Since the determination of risk factors could be effective in early diagnosis and consequent treatment, this study was carried out to determine some risk factors of breast cancer. Materials and Methods: This case- control study was carried out on 102 cases (referring to Motahari clinic) and 278 control (selected randomly out of 985 women who were healthy according to mammography in population based on screening study in Shiraz). Data were collected through interview and questionnaires and importance of different factors was evaluated through oddʹs ratio. Results: Unstandardized risk factors increasing the potency of breast cancer significantly according to correlation intensity were: age, parity (zero), Socioeconomic status, age at first full-term pregnancy, marital status, lack of breast feeding (P=0.05). Menarche and menopause were no significant risk factors. While after standardization of socioeconomic status and marriage age their relationship with breast cancer remained significant, though breast feeding lost its protective effect. Conclusion: Since there is no screening program using mammography, as routine in Iran, along with educational development we suggest performance of screening at least in above mentioned high risk groups. In order to clarify other risk factors more research is recommended.