بررسي مقايسه اي شاخص هاي ذخيره تخمدان در تشخيص زودرس بيماران با پاسخ ضعيف به داروهاي محرك تخمدان

Evaluation Criteria for Prediction Ovarian Response to COH in IVF/ICSI

one of the most challengeable issues in reproductive medicine is management of patient who poorly response to ovarian stimulating drugs. IVF/ICSI one of the methods that has been used in infertility with different ethiology. Because of limited success, high expense and stress in treatment , multiple endocrine tests and sonography have been done by infertility center to prediction of ovarian function. It would be clinically and economically helpful if there were better methods for prior assessment of likelihood of an inadequate ovarian responses. In prospective case control study, Data include age, duration of infertility, ethiology , ovarian volume and FSH, Estradiol in 3rd of menstrual collected from 54 woman <42 y without history of surgery on ovaries and FSH<20 who candidated for IVF/ICSI . Results included number of follicle, duration of stimulation and rate of pregnancy analyzed with SPSS. In point of response to COH patients divided two group, 36 case with good responses and 18 case with poor responses(lesser than 4 follicle ). Age, duration, and ethiology of infertility, FSH>12 ,Estradiol >80 and ovarian volume < 3 cm^ was not significant different in two groups.