بررسي ميزان كروم سرم خون افراد ديابتي مراجعه كننده به مركز ديابت دانشگاه علوم پزشكي شهيد صدوقي يزد

STUDY OF THE BLOOD CHROMIUM LEVELS OF DIABATIC PATIENTS REFERRING TO THE DIABETIC RESEARCH CENTER OF YAZD

Diabetes is one of the most prevalent metabolic disesaes . It is a metabolic disorder , and leading fifth cause of mortality in the west .The diabetes international federation estimates that there are more than 100 milion diabetic individuals world wide. In Iran , more than two milion people suffer from diabetes. Prevalence of diabetes in some parts of Iran , especially in Yazd is high. Deficiency of chromium was observed in some societies with special food habits, especially in some geographical areas. This research was therefore necessary. Chromium is considered an essential food and also an essential part of glucose tolerance factor. It is (also an important factor) for activating insulin in removing glucose from cells. This research was carried out to evaluate the blood serum chromium levels of diabetic indiviuals who refered to the diabetic center of Shahid Sadoughi University of medical university on the basis of age and sex. They were compared with group of IGT and control. 370 diabetic patients participated in this study . They were divided into four groups of IDDM , NIDDM, IGT and control. Fasting blood sugar (FBS) & glycosylated hemoglobim (HBAIC) were measured. Chromium concentration was measured by Atomic Absorption. Serum chromium concentration in diabetic patients (IDDM mean = 0.096± 0.002 p g/l) , (NIDDM mean = 0.097± 0.002 Miog/l),IGT group (Mean=0.17± 0.002 Miog/l) were significantly lower than control groups (mean =0.24± 0.002 Miog/l) (P=0.004). Furthermore, a negative correlation was found between FBS and chromium, HBAIC and chromium in diabetic patients (NIDDM r = -0.110) , IGT group (r= -0.176) and control (r= - 0.234). But no correlation was observed in IDDM patients . There is a positive correlation between FBS and HBAIC in all groups. It is recommended that estimation of chromium levels in Diabetic patients is a good guide for control of diabetes.