مقايسه حساسيت باكتريهاي كاپوفيل پريودنتوپاتوژن به آنتي بيوتيك هاي باكتر يوسيد و باكتريواستاتيك

Comparison of Capnophilic and Periodontopathogenic bacteria in their sensitivity to bactericidal and bacteriostatical antibiotics

Background & Aim: Periodontal infection is the main cause for disease of the periodontium which is known as one of the most common of all diseases in human. Periodontal disease is broadly subdivided into two main categories: Gingivitis and Periodontitis. Periodontitis is generally associated with the age of its onset but also can be appeared by the effect of bacteria present in the pockets surrounding the teeth. The purpose of this study was to isolate capnophilic and periodontopathogenic bacteria and compare their sensitivity to some bacteriocide and bacteriostatic antibiotics. Materials & Methods: In this descriptive study, 513 capnophilic and periodontopathogenic bacteria were isolated from 405 specimens (206 cases in 1993 and 200 cases in 2001) of patients by culture method under capnophilic condition. Sensitivity of isolated bacteria to bacteriocide and bacteriostatic antibiotics were investigated by Kirby-Beuer method. Results: The Frequency of isolated capnophilic and periodontopathogenic bacteria in 1993 and 2001 were Actinobacillus actinomycetemcomitans 76 (31%), 96 (35.8%), Eikenella corrodens 71 (29%), 94 (35.1%) and Capnocytophaga 98 (40%), 78 (29.1%), respectively. Sensitivity of isolated periodontopathogenic bacteria to bacteriocide and bacteriostatic antibiotics including ampicillin, chloramphenicol, erythromycin oxitetracycline and penicillin G was found to be lower in 2001 than 1993. Conclusion: A resistance sign of assessed microorganisms are seen to some of bacteriocide and bacteriostatic antibiotics. It is therefore suggested to stop irrelevant antibiotic therapy.