مصرف داروهاي ضدتيروييد متوسط مادران شيرده هيپرتيروييد براي فرزندان آنان بي خطر است

USE OF ANTITHYROID MEDICATIONS IS SAFE FOR LACTATING WOMEN AND THEIR BREAST-FED INFANTS

Hyperthyroidism may present,recur,or accelerate during the postpartum period in the majority of the females. Management of thyrotoxic lactating women has been a subject of controversy and until the last decade, antithyroid medications had been prohibited in thyrotoxic lactating mothers. In the last 20 years, the concentration of antithyroid drugs in the milk of lactating women was reevaluated and clinical studies showed that propylthiouracil and methimazole could be administered safely to mothers,without deterioration of thyroid function in the breast - fed infants.Even when serum TSH is increased in a methimazole treated - mother, T4,T3,and TSH concentrations are normal in her breast -fed infant.Between the ages of 4-8 years,all infants who were breast fed by methimazole - treated mothers had normal physical growth, thyroid function tests and their global IQ and 11 subsets of IQ were comparabfe to control infants. this research proves the innocuousness of breast feeding infants by thyrotoxic lactating mothers taking antithyroid medications and physicians can advise lactating mothers to continue breast feeding of their infants.