اثر ژل پيروكسيكام به همراه اولتراسوند بر استيوآرتريت زانو

The Effect of Pyroxicam Gel with Ultrasound on the Knee Osteoarthritis

Since pain is the main debilitating cause of knee ostheoarthritis , application of local analgesics have been the center of attention to avoid their systemic complications especially since ultrasound application can enhance their local absorption . This study was conducted to determine the effect of pyroxicam gel (which is very common in our country ) with ultrasound on pain soothing in patients with knee ostheoarthritis . This double blind clinical trial was experimentally conducted on 90 affected knees taking inclusion - exclusion criteria into consideration . Patients were randomly assigned into experimentul and control groups , receiving "pyroxicam + ultrasound" and "ultrasound gel + ultrasound" respectively , for five successive days . Before and after treatment , Knee Pain Scale , Visual Analog Scale and Investigator Total Assessment were checked . The difference of these three indicators before and after the treatment were statistically analyzed using t-test , paired t-test and Mann Withney test . Findings revealed that all three indicators suggested a decrease in pain , which was significant in "Pyroxicam + ultrasound" group (P >0.0001) . The two groups were homogeneous as for their sex , age and BMI . It was finally concluded that "pyroxicam with ultrasound" is more effective than ultrasound alone , and hence it is recommended for routine physiotherapy .