رابطه ميان غلظت ايمونوگلوبولين ها با وضعيت پالب دندان

Correlation of immunoglobulins with Different States of Dental Pulps

Background & Aim: The presence of immunocompetent cells and various classes of immunoglobulins in inflamed pulps, indicates that host immune responses could participate in the pathogenesis of pulpitis. The purpose of this study was to determine the changes of immunoglobulins in the supernatant fluids of the explant cultures of various states of dental pulps. Material and Methods: For this purpose pulps of impacted teeth: were culyure with also healthy erupted teeth, teeth with irreversible symptomatic pulpitis; and irreversible asymptomatic pulpitis were cultured. The amounts of various classes of immunoglobulins were measured by SRID method. Results: The presence of 1gG in the above states were 62.5%; 26.7%; 60%; and 100% with average concentration of 833.5±944.5; 81.1+206; 23.6+30.6; and 786.5+799.5 mg/100ml ,respectively. The differences between between these groups regard to concentration of 1gG were significant (p< 0.002). The presence of IgA were observed in 50%; 6.7%; 10%; and 100% with average concentration of 213.1+257.6; 31.1+121.6; 4.25+13.3; and 282.7+212.2 mg/I00ml, respectively. There was also significant differences between the above groups for their IgA concentration (p< 0.001). IgM was present in 6.2%; 26.7%; 30%; and 0% with average concentration of 0; 54.7+132.2; 20+32.7; and 0 mg/100ml, respectively and the differences between these four groups were significant (p< 0.05). Conclusion: In conclusion, there are significant differences between the pulps of impacted and healthy erupted teeth regard to presence and amounts of immunoglobulins.