بررسي مقايسه اي تلقيح داخل رحمي و مقاربت طبيعي در درمان نازايي به علت مايع مني غيرطبيعي

A Comparative Study of Intrauterine Insemination and Natural intercoursein the Treatment of Infertility Caused by Subnormal Semen

This study is intended to determine whether intrauterine insemination (IUI) after ovarian stimulation with clomiphen citrate (cc) gives a better pregnancy rate than natural intercourse in couples with subfertility because of subnormal semen . This study is a prospective randomized controlled trial . Couples with subnormal semen as only identifiable cause of subfertility . In control cycles , the couples had natural intercourse . In IUI cycles , IUI was performed after ovarian stimulation with cc and human chorionic gonadotropin . The clinical pregnancy rates and complications of IUI cycles and control cycles were compared . The results indicated that there were four clinical pregnancies in the 32 IUI cycles , whereas there was no clinical pregnancy in the 32 control cycles . The clinical pregnancy rate in IUI cycles (12.5% per cycle) was significantly higher than that in control cycles (0%) . None of the patients developed ovarian hyperstimulation syndrome in IUI cycles . Therefore , intrauterine insemination after ovarian stimulation with cc is useful in treatment of subfertile couples with subnormal semen .