بيماري كمخوني داسي شكل گلبولهاي قرمز خون و آبستني

PREGNANCY AND SICKLE CELL HEMOGLOBINOPATHY

It is generally found that the increased fetal loss in mothers with sickle cell disease, it attributed to increased incidence of abortion , intrauterine growth retardution, perinatal and infant death, published reports indicated a previous abortion rate of 50% in (SS) disease. However with imporoved maternal and fetal care, perinatal death has been reduced to 12.2% ( hemoglobin SS). In a previous studies in Iran, sickle cell was shown that to be relativly milder in clinical manifestations. Those findings have been attributed to presence of a high percentage high percentage of FHb. We reported here 5 cases of (SS) and sickle - Beta thalassemic pregnant women with relativly high percentage of FHb and history of previous abortions, They complate the last pregnancy in Ahwaz Thalassemic Center and deliverd mature newborn through normal delivery or C/S at the 36-37 weeks of gestation. They did not have any clinical problams such as toximia - pregnacy, hypertesion, proteinuria or interautrine growth retardation. They treated by periodic regular prohylactic packed red cell transfusion during pregnancy if Hb became less than 8-9gr% or less 30% from normal baseline.