مقايسه شيوع انگل هاي گوارشي در بيماران HIV مثبت و ايدزي شهرستان خرم آباد در سال 86-1385

Comparison of the Prevalence oflntestinal Parasites in HlV-Positive and AIDS Patients in Khorramabad City in 2006-2007

, Background & Aims: Immunodeficiency virus (HIV) may lead to acquired immunodeficiency syndrome (AIDS) in human. Parasites are one of the most important causes of infectious diseases in patients with AIDS. The prevalence of these parasites varies based on the condition of hostʹs immune system and ʹthe stage of disease (HIYIAIDS). To compare the prevalence of opportunistic intestinal parasites a crosssectional study was carried out on 306 HIY positive and AIDS patients in Khorrarnabad city. Methods: After selecting the samples by census and availability sampling methods, planned questionnaires were completed and three stool samples were collected from patients. Then direct smear, formalin-ether concentration techniques and modified acid fast (Kinione) and modified trichorome staining methods were carried out on all samples during 2006-2007. Moreover the relationship between different variables and infection by intestinal parasites were examined. For description and statistical analysis t-test and Chi-square test were used. Results: The prevalence of intestinal parasites in HIY-positive and AIDS patients was 19.6% and 50% respectively. There was a significant relationship between HIY /AIDS and species of intestinal parasites (P< 0.001). Conclusion: Higher prevalence of intestinal parasites in patients with AIDS compared to HIY-positive individuals indicates higher immune system deficiency and more susceptibility to intestinal parasitic infections (specially opportunistic parasites) and reflects the necessity ofprevention, screening, diagnosis and treatment programs for these patients.