بررسي ارتباط پارامترهاي اسپرم (تحرك-تعداد و مورفولوژي) و منبع برداشت اسپرم بر پيامد درمان تزريق داخل سيتوپلاسمي اسپرم

A study on the relation of sperm parameters and sperm origin on the outcome of cytoplasm sperm injection (ICSI) in infertile couples

Introduction: Microscopic examination of semen is a mandatory procedure when conducting investigations on an infertile couple and the results of semen analysis influence the choice of treatment methodologically. Recent data indicate that sperm morphology assessed according to the Kruger criteria is classified according to the three predictive categories: excellent prognosis> 14% normal morphology spermatozoa .good prognosis 4-14% and poor prognosis <4%, which is an excellent biomarker of sperm dysfunction and in predicting the outcome of ICSI. On the contrary, some other studies have indicated thai the outcome of ICSI does not depend on strict morphology , This study was carried out to investigate the relation of semen parameters (count, mobility and morphology) and sperm origin on the outcome ofICSl. Materials & Methods: This cross-sectional study was carried out on 500 medical records of infertile couples referred to the Mehr Infertility Treatment Institute ,under going IeSI procedure with non probability samplings. The research variables included age, cause and type of infertility, sperm parameters (count, mobility and morphology), sperm origin, numbers of retrieved ova, numbers of transferred embryos and embryo implantations and pregnancy rate{PR). After data collection, statistical analysis was carried out using SPSS.IO software and statistical test of Tvtestand x.2 . Findings: The results showed that overall PR achieved by reSI procedure was J9%{195 out of 500 cyclcs).A significant relation was discovered between the average of the women and the outcome of JeSI ; {pregnant: 29.6±5.6 versus non pregnant : J 1.6±5.5years).The relation between cause and duration of infertility, spenn parameters (count, mobility and morphology) and sperm origin with the outcome of ICSI was not statistically proved as significant (P>0.05). Conclusion: It seems that sperm parameters and sperm origins canʹt be regarded as reliable prognostic factors in foretelling successful pregnancies through resl procedure.