عنوان مقاله :
مقايسه يافته هاي سونوگرافي و تست هاي عملكرد كبدي در مبتلايان به هپاتيت ب مزمن HBE aG منفي و HBE aG مثبت
عنوان به زبان ديگر :
Comparison of Sonographic findings and Liver Enzyme Status
in Patients with HBeAg-Negative and HBeAg-Positive Chronic
Hepatitis B
پديد آورندگان :
بهاري، علي نويسنده گروه داخلي،دانشكده پزشكي،دانشگاه علوم پزشكي و خدمات بهداشتي درماني زاهدان Bahari, A , خزاييان، صفورا نويسنده دانشكده پزشكي، دانشگاه علوم پزشكي و خدمات بهداشتي درماني زاهدان KHazaiean, S , هاشمي، حامد نويسنده دانشكده پزشكي، دانشگاه علوم پزشكي و خدمات بهداشتي درماني زاهدان Hashemi, H , صانعي مقدم، اسماعيل نويسنده مركز تحقيقات سازمان انتقال خون ايران و پايگاه منطقه‌اي آموزشي زاهدان Saneie Moghadam, E , شهرياري، حسين نويسنده دانشگاه علوم پزشكي و خدمات بهداشتي درماني زاهدان Shahriari, H , رخشاني، فاطمه نويسنده مركز تحقيقات ارتقاء سلامت، دانشگاه علوم پزشكي و خدمات بهداشتي درماني زاهدان Rakhshani, F
كليدواژه :
سونوگرافي كبد , شاخص عملكرد كبد , HBE AG , Chronic hepatitis B , Liver function test , HBeAg negative , HBeAg positive , هپاتيت ب مزمن
چكيده لاتين :
Background: Virologic parameters and liver enzymes are generally measured to determine
prognosis of hepatitis B. The present study was conducted to determine the liver function indices
and sonographic findings of chronic hepatitis B (CHB) in HBeAg-negative and HBeAg-positive
patients.
Materials and Methods: This Historical Cohort study was conducted on 234 patients with active
CHB (117 HBeAg-negative and 117 HBeAg-positive) in 2007. The patients who were referred to
Hepatitis Clinic of Blood Transfusion Organization were included in the study.
Results: One hundred eighty patients were male, majority of them were resident of Sistan
province and married. The mean age of patients with CHB HBeAg-negative was more than patient
with CHB HBeAg-positive (38.03±11.1 vs 28.77±9.8). There were no significant difference in
Bilirubin, Albumin, ALT and AST levels and also PT between the two groups, but a significant
difference in sonographic findings of liver was demonstrated between two groups.
Conclusion: Based on our results, it is recommended to use other diagnostic indices including
virologic parameters and histopathology to distinguish CHB patients.
كلمات كليدي :
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