بررسي مقايسه اي اثرات ترامادول با ولتازن در درمان كوليك كليوي

comprison of tramadol and voltaren in the treatment of acute renal colic

tv; over the world, renal colic is one of the most common causes of referring to emergency units, The first therapeutic step is treatment of pain by using cJi ffercnt drugs, The aim of this study is to compare the therapeutic effects of a single dose of Trarnadol (100 mg intramuscular) and single dose of Vullaren (75mg intramuscular) in treatment of acute renal colic. Materials and Methods: In this double blind clinical trial study in the year 2004 at Urology Department of Ghaem Hospital, 100 patients (84 men and 16 women, mean age 35.9 years, range 18-60) with acute renal colic were studied. KUB, urinalysis and ultrasonography were done in all cases. The patients were randomly assigned to receive either 100 mg of trarnadol 1M (48 patients) or 75mg of voltaren TM (52 patients). The patientsʹ pain was evaluated before injection, 30 and 60 minutes after injection by Visual Analogue Scale (VAS) and Data was analyzed by t- lest, ManWhitney and K-square test. Results: VAS pain scores in hath groups wert: similar at the beginning of the study (p=0.39). Within 30min; pain was markedly improved in 4J patients (78.8%) of voultaren group and 28 patients (5lJ,3%) of lramadol group (p<0.05). After 60 minutes, 43 patients (82.7%) in voltaren group and 31 patients (64,6%) in tramadol group showed obvious improvement. No serious side effect was reported with use of either treatment. Only 5 patients in tramadol group showed nausea and vomiting, vertigo and weakness. Conclusion: Voltarcn can be used effectively in treatment of acute renal colic and it has earlier onset of action and prolong effect in comparison with tramadol.