مقايسه سطح CRP و ESR در زنان مبتلا به سندرم تخمدان پلي كيستيك و گروه شاهد

Comparison of the CRP and ESR Levels between Women with Polycystic Ovarian Syndrome and Control Group

Introduction: Low grade chronic inflammation can predict persons with risk of coronary heart disease (CHD) and type 2 diabetes. Women with Poly cystic ovarian syndrome (peaS) are insulin resistant and have high risk for CHD and type 2 diabetes. Objective: Evaluate the correlation between low grade chronic inflammation and peos. Materials and Methods: This case-control study was done on 27 women with peos who were defined base on irregular menstruation and elevated androgen (clinical hyperandrogenism or byperandrogenemia) and 27 healthy women who were matched 35 a control group base on similar body mass index (8Ml) and age. CRP, ESR. SHBG and Testosterone were measured in all women in both groups. Determine of insulin resistance was assessed by estimation the ratio ofFBS/ to Fasting insulin. The mean of testosterone. SHBG, eRP, ESR and the ratio of FBSI to Fasting Insulin in the two groups were compared by t- test and the correlation between BMI, testosterone. SHBG and ratio ofFBSI to §sling insulin with CR.P and ESR were analyzed by Pearson correlation coefficient Results: The finding showed: the mean of eRP was significantly difference in two groups and it was more in case group. (549/67 ± 378138 & 2566 ± 10/22, P