نقش عوامل رشد اندوتليومي عروقي و عوامل مهار كننده آن ها در نورگ زايي چشمي

Role of Vascular Endothelial Growth Factors in Ocular Neovascular Diseases

The most important progress in the field of retinal diseases during recent years might be the introduction of pharmacotherapy. Age-related macular degeneration for instance was an irreversible disease leading to permanent anatomical and functional changes in the macula up to the previous decade; however, the use of anti-vascular endothelial growth factor agents (anti-VEGFs) not only stops the progression of the disease but also improves vision in a significant proportion of patients. Ophthalmologists now deal with numerous questions about anti-VEGF agents. This review indicates how VEGFs act in normal and pathological conditions in the eye and introduces the most important agents in this category of ocular drugs.