ارتباط PH واژن و سطح سرمي هورمون تحريك كننده فوليكول در زنان يائسه

Correlation between Vaginal pH and Serum Follicle Stimulating Hormone in Menopausal Women

Introduction: In the absence of vaginitis, elevated vaginal pH may indicate low circulating estrogen levels. So determining vaginal pH values can be a simple and low cost diagnostic tool for menopause. Aim of this study was to examine the correlation between serum follicle stimulating honnone and v aginal pH in menopausal women. Materials and Methods: This is an analytical cross-sectional study carried out on 100 menopausal women referring to gynecologic unit at Alzahra hospital (Rasht, north of Iran).Women who had no menstrual period during the last 1 year, without vaginitis, estrogen replacement therapy, use of vaginal drugs or douches and did not have coitus during the 2 days before the examination were included in the study. Vaginal pH values were assessed by Nitrazine papers. Serum follicle stimulating hormone was measured, and body mass index V calculated. The collected data were analyzed by SPSS software version 10. Statistical tests such as chi-square, and hi-variate correlation were used. Results: The mean age of women was (54.92+8.3) years. There were a direct and significant correlation between serum follicle stimulating hormone and vaginal pH (r= 0.245), vaginal pH and age (r=0.004). and vaginal pH and duration of menopause (r=-0.0125). Also there was straight and significant correlation between serum follicle stimulating hormone and vaginal pH among women whose body mass indices were less than 25 or 25-29.9 kg/m\ and women with postmenopausal periods more than 1 year(P<0.05) Conclusion: Our study showed poor correlation between vaginal pH and serum follicle stimulating honnone in menopausal women(i^0.245).